Water quality concerns the physical, chemical, and biological factors that could negatively impact human health through its consumption, potentially causing infectious and chronic diseases due to immediate or prolonged exposure. In this context, the objective of this study is to identify diseases that are correlated with the quality of drinking water according to the literature. A systematic review was carried out considering academic and scientific documents from the last 6 years, including peer-reviewed research articles, books, and technical documents, such as standards and regulations related to public health and water quality. Subsequently, these results were applied to a case study from Tonosí (a district in Panama), where a drinking water quality assessment project was developed over the past two years including physicochemical, biological, inorganic chemical, and organic chemical analyses on drinking water during the rainy and dry seasons. Forty-five documents were obtained from the literature review and are presented in tables relating to diseases and water quality parameters. Based on the drinking water quality assessment results from Tonosí, the levels above and below the permissible range—according to the DGNTI-COPANIT 21-2019 Technical Regulation adopted by Panama as a drinking water quality standard—and the diseases associated with the parameters evaluated (in accordance with the literature review) are presented. The results show that there is a possible relationship between some of the water quality parameters and cases of gastrointestinal diseases in the area; however, more in-depth research and statistics at the national level are needed on the health of the population.
