2017
DOI: 10.4049/jimmunol.198.supp.226.8
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Diclazuril treatment ineffective at preventing Equine Protozoal Myeloencephalitis relapse in established mouse model.

Abstract: The debilitating and potentially fatal neurologic disease, Equine Protozoal Myoencephalitis (EPM), is one of the most common neurologic diseases seen in the equine population of the United States. Disease develops as a result of unintentional ingestion of the pathogenic parasite, Sarcocystis neurona. Treatment options consist of the anticoccidial drug Diclazuril and numerous other antiprotozoal drugs. Weeks to months after cessation of antiprotozoal drug treatment and corresponding neurologic improvement, hors… Show more

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