2009
DOI: 10.1016/j.ijpharm.2009.01.024
|View full text |Cite
|
Sign up to set email alerts
|

Diclofenac nanosuspensions: Influence of preparation procedure and crystal form on drug dissolution behaviour

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

2
44
1
1

Year Published

2011
2011
2018
2018

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 96 publications
(48 citation statements)
references
References 18 publications
2
44
1
1
Order By: Relevance
“…The dissolution medium used was freshly prepared using 0.1 N HCL (pH 1.2). Dialysis membrane, previously soaked overnight in the dissolution medium was tied to one end of a specifically designed glass cylinder (open at both the ends) (Pandya et al 2010;Lai et al 2009). Five milliliter of the formulation was accurately placed into this assembly.…”
Section: Drug Release Studymentioning
confidence: 99%
“…The dissolution medium used was freshly prepared using 0.1 N HCL (pH 1.2). Dialysis membrane, previously soaked overnight in the dissolution medium was tied to one end of a specifically designed glass cylinder (open at both the ends) (Pandya et al 2010;Lai et al 2009). Five milliliter of the formulation was accurately placed into this assembly.…”
Section: Drug Release Studymentioning
confidence: 99%
“…Since CS nanoparticles are positively charged and due to their mucoadhesive properties, they are widely used in colon and mucosal delivery, cancer therapy and target drug delivery (4). Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that is used via different routes such as oral, rectal, parenteral, topical and ocular administration (5). Diclofenac-loaded chitosan nanoparticles are expected to be potential carriers for ophthalmic drug delivery.…”
Section: Introductionmentioning
confidence: 99%
“…3 µm (at a pressure of 1500 bar). 1,19 The production process is discontinuous with LAB 40, the system needs to be dismantled before each homogenization cycle which makes production time consuming. APV LAB40 has biggest advantage of extremely low sample volume, which is very important for expensive or for limited availability compound (e.g.…”
Section: Lab Scale Production Using Apv Lab 40mentioning
confidence: 99%
“…In addition, the production technology should allow ease of scale up from lab to industrial scale. 1,2 Normally, from moving up in batch size by a factor of 10 to 100 various problems occur in obtaining a product of the same specifications. 3 Many successful formulations at lab scale might fail during scaling up trials.…”
Section: Introductionmentioning
confidence: 99%