Diclofenac Suppository as a Preemptive Analgesia in Ultrasound-guided Biopsy of Prostate: Randomized Controlled Trial

Haroon, Naveed; Ather, M Hammad; Khan, Salma; Kumar, Pirkash; Salam, Basit

doi:10.1016/j.urology.2015.04.044

Cited by 9 publications

(8 citation statements)

References 8 publications

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“…No patients were concerned about vertigo, headache, nausea, or vomiting. However, the number of biopsy cores was clearly higher in our study: a mean of 18,5 cores was performed, whereas other studies did between 5,6 and 14 cores only ( 16 , 20 , 21 ).…”

Section: Discussioncontrasting

confidence: 82%

“…Several studies show its efficacy in managing pain during labor ( 4 ), burn dressing changes ( 5 ), periodontal scaling and root planing procedures ( 6 ), and for children undergoing medical procedures ( 7 ). Several methods of analgesia have been proposed ( 8 – 11 ), including periprostatic basal ( 12 ) or apical nerve block ( 13 ), topical anesthesia with lidocaine ( 14 ), nitrous oxide-oxygen inhalation ( 15 ), diclofenac suppository ( 16 ), or sedation ( 17 ). The national committee guidelines ccAFU currently recommend the periprostatic nerve block (PPNB) with or without topical gel instillation ( 18 ).…”

Section: Introductionmentioning

confidence: 99%

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Impact of virtual reality on pain management in transrectal MRI-guided prostate biopsy

Perenic,

Grember,

Bassard

et al. 2023

Front. Pain Res.

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BackgroundThe beneficial effect of virtual reality (VR) on pain management in the context of transrectal MRI-guided prostate biopsy is not well established. However, it remains unclear whether an adjunctive of VR also improves pain management. This study aimed to evaluate the impact of VR as adjunctive in pain management in transrectal MRI-guided prostate biopsy (PB).MethodsWe retrospectively evaluated the pain intensity incidence in the 153 patients with PB indication (of which 102 were naïve of PB) who were admitted to our hospital since the acquisition of the Healthy Mind virtual reality headset on 19 January 2021.ResultsBaseline characteristics of patients who received local anesthesia with 1% lidocaine periprostatic nerve block (PPNB) (Group SOC, N = 78) and patients who received VR associated with PPNB (Group VR, N = 75) were largely similar. One PB with general anesthesia was excluded. The mean pain score at day zero was respectively 3.4 (±2.5) and 2.9 (±2.3) for SOC and VR (p = 0.203). However, the mean pain score at day zero was significantly lower in naïve PB patients with VR [2.7 (±2.0)] than in naïve PB patients with SOC [3.8 (±2.5), p = 0.012] when patients were stratified in PB status. Similar results were found on day 3 for the analysis including naïve-PB patients with SOC vs. with VR [0.4 (±2.5) vs. 0.2 (±2.0); p = 0.023)].ConclusionsThe pain intensity was significantly lower in naïve PB patients with VR than in naïve PB patients with SOC. There were no side effects from VR and tolerability was excellent.

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Section: Discussioncontrasting

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Impact of virtual reality on pain management in transrectal MRI-guided prostate biopsy

Perenic,

Grember,

Bassard

et al. 2023

Front. Pain Res.

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“…Previous studies demonstrated the efficacy of preoperative oral administration of nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase-2 (COX-2) inhibitors, 1 gabapentin and pregabalin, 3,14 and other drugs. Preemptive intravenous administration of ketorolac, 25 ketamine, 49 propofol or remifentanil, 26 as well as suppository of diclofenac 29 also reduced postoperative pain intensity. The latest nonconventional methods of preemptive analgesia are frequency rhythmic electrical modulation system, 2 electroacupuncture, 60 and transcutaneous electrical nerve stimulation (TENS).…”

Section: Discussionmentioning

confidence: 97%

Preemptive Local Anesthesia in Ankle Arthroscopy

Liszka

Gądek

2016

Foot Ankle Int.

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“…The PGE2 enhances the pain receptor’s sensitivity to algesic substances such as bradykinin and substance P 29. Centrally, prostaglandins act in the spinal cord and higher centers to promote the transmission of pain signals to the brain 30. A study by Silva et al,31 was carried out to investigate the effectiveness of ibuprofen and etodolac for controlling pain, swelling, and trismus following surgical removal of the lower third molars.…”

Section: Discussionmentioning

confidence: 99%

Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations

Gazal¹,

Al-Samadani²

2017

SMJ

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Objectives:To compare the effectiveness of different oral analgesics for relieving pain and distress in adults following the extraction of teeth and deep cavity preparations under local anesthesia.Methods:This randomized controlled study was conducted between November 2015 and May 2016. One hundred and twenty patients were randomly allocated to 3 groups. Forty patients were in the paracetamol (1 gram) group, 40 in the ibuprofen (400 mg) group and 40 in the diclofenac potassium (50 mg) group. Evaluation of the post extraction and deep cavity preparations pain was made by patients immediately postoperatively, 2, 4 and 6 hours postoperatively on standard 100 mm visual analogue scales (VAS). Furthermore, each patient was observed preoperatively and immediately postoperatively for signs of distress by using a 5 point face scale.Results:There were significant decreases in mean pain VAS scores for diclofenac potassium group compared to paracetamol and ibuprofen groups at 4 hours postoperatively (one-way Analysis of Variance: p=0.0001, p=0.001) and 6 hours postoperatively (p=0.04, p=0.005). Changes in distress scores from the preoperative score to the postoperative score were made using the paired sample t-test. There were significant decreases in distress scores between the preoperative and postoperative scores (p=0.0001).Conclusions:Diclofenac potassium was more effective than paracetamol or ibuprofen for reducing postoperative pain associated with tooth extraction and deep cavity preparation. Patients’ distress levels can be alleviated by using preemptive analgesics.

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Diclofenac Suppository as a Preemptive Analgesia in Ultrasound-guided Biopsy of Prostate: Randomized Controlled Trial

Cited by 9 publications

References 8 publications

Impact of virtual reality on pain management in transrectal MRI-guided prostate biopsy

Impact of virtual reality on pain management in transrectal MRI-guided prostate biopsy

Preemptive Local Anesthesia in Ankle Arthroscopy

Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations

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