Dicyclohexylcarbodiimide as a simple and specific fluorogenic spray reagent for some di- and tricarboxylic acids

Fluorometric determination of citric and aconitic acids with dicyclohexylcarbodiimide

“…DCC and solvents were purchased from Merck (Darmstadt, West Germany) and used as received. Other materials were the same as described previously (7).…”

“…Specificity of the Present Methods. Although it has been investigated on TLC plates in previous paper (7), the specificity of the reactions of DCC with acids in acetic acid solution was reinvestigated.…”

“…With the standard procedures 50 compounds with one to three carboxyl and related groups, as used in the previous paper (7), were examined at the 10 µ level. The result shows that, except those given in Table II, salts of these acids and cis-aconitic anhydride, all were negative to DCC in acetic acid solution.…”

“…In the previous paper (7), the author has established a new detection method for some diand tricarboxylic acids on TLC plates and papers with dicyclohexylcarbodiimide (DCC) as a spray reagent. In this paper, the author, applying the same reagent, describes a new fluorometric method for specific determination of citric and aconitic acids.…”

Dicyclohexylcarbodiimide as a cleaving agent for colorimetric determination of pyridyl and pyrimidinyl compounds

“…Carbodiimides are widely used as excellent coupling or dehydrating agents in synthesis (1)(2)(3) and analysis (3)(4)(5)(6)(7)(8)(9)(10). Recently, Wilchek and co-workers (10,11) have demonstrated their cleaving activity on pyridine (eq 1) and established a colorimetric method for the determination of carbodiimides (10).…”