“…A common sign of left ventricular failure in a polygraphic tracing consists in a prolongation of the isometric contraction, in particular of the isometric phase proper, in the shortening of the isotonic part of the contraction and reduction of the mechanical quotient. These changes are interpreted as an expression of a per turbation of the contractility of the heart muscle associated with a slowing down of the rise of the intraventricular pressure and with an earlier relaxation of the heart muscle tonus towards the end of the systole (see paragraph 2 C) (14,17,27). This character istic of changes was encountered in particular in complicated hypertensive disease, in ischaemic heart diesase, in exudative peri carditis, etc.…”