Die Elliptocytose (Ovalocytose) und ihre klinische Bedeutung

Hereditary Elliptocytosis and Hyperhaemolysis

“…It seems reasonable to conclude that in our patients with elliptocytosis hyperhaemolysis with adequate compensation by increased erythrocyte production was the rule. As we mentioned, Lambrecht (21) used the degree of haemolysis as criterion in dividing elliptocytosis into A : a latent form; B: a compensated form; C: a noncompensated form.…”

“…Lambrecht (21) and Leitner (22) In every smear, we evaluated at least 200 red cells (from the same microscopic field).…”

“…Clinical symptoms which may occur in patients with elliptocytosis can often be traced back to hyperhaemolysis. Lambrecht (21) presented the following classification according to the degree of haemolysis in elliptocytosis.…”

Hereditary Elliptocytosis

“…It is characterized by the presence of generally more than 20-25%, and often more than 90%, of oval and elliptical erythrocytes in stained blood samples [30,31]; moreover, it is generally characterized by normal values of MCV, MCH and MCHC, and often by increased osmotic fragil ity of RBC [18],…”