Die Entwickelungsmechanik der Nervenbahnen im Embryo der Säugetiere

Hensen, V.

doi:10.5962/bhl.title.86372

Cited by 13 publications

(2 citation statements)

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“…(B) Fig. IVa, p. 32 in Hensen ( 1903 ) showing a transverse section with what Hensen believed to be the precursor of the nephric duct arising from a cell mass in the ectoderm; the mass grows ventrad towards the mesoderm and then becomes detached (our boxes a and b ). (C) Plate XI (III) in His ( 1865a ) A – D (from bottom to top) are sections from the same chicken embryo showing what His thought was the precursor of the nephric duct (Urnierenfalte, Unf .).…”

Section: Wilhelm H Is's Early Researchmentioning

confidence: 97%

The revolutionary developmental biology ofWilhelmHis,Sr.

Richardson

Keuck²

2022

Biological Reviews

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Swiss-born embryologist Wilhelm His, Sr. was the first scientist to study embryos using paraffin histology, serial sectioning and three-dimensional modelling. With these techniques, His made many important discoveries in vertebrate embryology and developmental neurobiology, earning him two Nobel Prize nominations. He also developed several theories of mechanical and evolutionary developmental biology. His argued that adult form is determined by the differential growth of developmental primordia. Furthermore, he suggested that changes in the growth parameters of those primordia are responsible for generating new phenotypes during evolution. His developed these theories in his book 'Our Bodily Form' (Unsere Körperform). Here, we review His's work with special emphasis on its potential importance to the disciplines of evolutionary developmental biology (evo-devo) and mechanobiology.

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Section: Wilhelm H Is's Early Researchmentioning

confidence: 97%

The revolutionary developmental biology ofWilhelmHis,Sr.

Richardson

Keuck²

2022

Biological Reviews

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“…Around 1900, the development of the nervous system and of nerve fibers were hotly debated. Hensen, studying the development of nerves in the tail of the tadpole by hand sectioning and hardening in acidic solutions, argued that the outgrowth of adult nerve fibers adapted to the needs of the body as a whole (Hensen, , ; see also Jacobson, ): as they separated, cells and tissues laid down conduction paths, some of which developed into adult nerve fibers. H. Held supported Hensen's syncytial theory, holding that the nervous system developed by a vis a tergo that drove extending neurons to contact other cells.…”

Section: Interlude: Tissue Culture and Nerve Originsmentioning

confidence: 99%

From experimental zoology to big data: Observation and integration in the study of animal development

Bolker

Brauckmann

2015

J. Exp. Zool.

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Our goal in this paper is to explore the nexus of experiment, observation, and environment in developmental biology, weaving together history and epistemology. We will not attempt a comprehensive treatment of each of these areas. Instead, we use the development of the Journal of Experimental Zoology (JEZ)-which marked its 110th anniversary this past year-as a lens through which to examine how issues of experiment and environment were articulated by some of its founders, and how central questions about how and where to study development continue to resonate a century later.The journal came into being in a tavern in Philadelphia on November 21, 1903. There E.B. Wilson, T.H. Morgan, and E.G. Conklin met to discuss the "the composition of the editorial board, the managing editor, the name, scope and policies of the new publication" (Harrison, '45, xiv). R.G. Harrison was shortly persuaded to serve as the managing editor-a position he held for more than 40 years. ABSTRACTThe founding of the Journal of Experimental Zoology in 1904 was inspired by a widespread turn toward experimental biology in the 19th century. The founding editors sought to promote experimental, laboratory-based approaches, particularly in developmental biology. This agenda raised key practical and epistemological questions about how and where to study development: Does the environment matter? How do we know that a cell or embryo isolated to facilitate observation reveals normal developmental processes? How can we integrate descriptive and experimental data? R.G. Harrison, the journal's first editor, grappled with these questions in justifying his use of cell culture to study neural patterning. Others confronted them in different contexts: for example, F.B. Sumner insisted on the primacy of fieldwork in his studies on adaptation, but also performed breeding experiments using wild-collected animals. The work of Harrison, Sumner, and other early contributors exemplified both the power of new techniques, and the meticulous explanation of practice and epistemology that was marshaled to promote experimental approaches. A century later, experimentation is widely viewed as the standard way to study development; yet at the same time, cutting-edge "big data" projects are essentially descriptive, closer to natural history than to the approaches championed by Harrison et al. Thus, the original questions about how and where we can best learn about development are still with us. Examining their history can inform current efforts to incorporate data from experiment and description, lab and field, and a broad range of organisms and disciplines, into an integrated understanding of animal development.

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Neuroblast versus sheath cell in the development of peripheral nerves

Harrison

1924

J of Comparative Neurology

198

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Die Entwickelungsmechanik der Nervenbahnen im Embryo der Säugetiere

Cited by 13 publications

References 3 publications

The revolutionary developmental biology ofWilhelmHis,Sr.

The revolutionary developmental biology ofWilhelmHis,Sr.

From experimental zoology to big data: Observation and integration in the study of animal development

Neuroblast versus sheath cell in the development of peripheral nerves

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