Die mechanische Hydronephrose und ihre Fähigkeit zur Rückbildung im Experiment

Holder, E.

doi:10.1007/978-3-642-94661-5_6

Cited by 7 publications

(1 citation statement)

References 10 publications

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“…Five methods have been described for instituting a state of reversible, ureteric obstruction in the experimental animal [1,5,10,11,14]. Four of the techniques were accompanied by serious complications [ 1 ,5,11,14].…”

Section: Introductionmentioning

confidence: 99%

A method for creating reversible ureteric obstruction in the primate

Evans

Candy

Veller

et al. 1998

J of Medical Primatology

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A technique has been developed for the establishment of a state of reversible, ureteric obstruction in the primate. Ten adult males had baseline 99mTc-DTPA renogram studies. A randomly selected ureter was totally occluded and obstruction confirmed on renogram. The occlusion was reversed and subsequent renograms confirmed recovery of activity in the obstructed kidneys of the eight animals who survived the reversal procedure. Seven were alive on conclusion of the study. Prevention of ureteric strictures was achieved with an intra-ureteric silastic tube. Autopsies demonstrated patency of every previously occluded ureter. This is the first study to be reported in primates, and the second overall, in which complete ureteric obstruction and its successful reversal has been confirmed on renogram using this surgical method. The technique is suitable for the study of the effect of reversible ureteric obstruction on renal function.

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Section: Introductionmentioning

confidence: 99%