Die Wirkung einmaliger, oral gereichter Äthanolgaben auf die Cholinesterase-, GOT-, GPT-, alkalische Phosphataseaktivität und den Vitamin A-Spiegel des menschlichen Blutes mit besonderer Berücksichtigung der Vergiftungen mit organischen Phosphorsäure-Insekticiden

Rengei, B; Mindszenty, L.; Ember, M; Csiszár, Bela

doi:10.1007/bf02114773

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T�dliche Vergiftungen mit Propoxur

1987

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The insecticide propoxur (2-isopropoxyphenyl-N-methylcarbamate) acts by blocking cholinesterase. This inhibition is fast and, unlike that brought about by organophosphorus compounds, reversible. The toxicity of propoxur to man is stated to be low compared with that of parathion. Only a small number of fatal intoxications have been published; at the Würzburg University Institute of Legal Medicine eight cases have been observed since 1978. In seven cases death occurred after deliberate oral ingestion of solutions of propoxur with suicidal intent, while in the other, intoxication was accidental, following inhalation of an aerosol containing propoxur. Organs and body fluids were investigated toxicologically and histologically. The results are presented and discussed. Special attention is paid to the combination of propoxur and alcohol.

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