Dielectric properties of nicotinic acid/methyl cellulose composite via “green” method for anti-static charge applications

Aim: This study aims to prepare a nanocomposite (HPMC/5-FL@GO) from hydroxypropyl methylcellulose (HPMC) and graphene oxide (GO) as biocompatible materials.The nanocomposite enhances the drug activity of immobilized 5-fluorouracil (5-FU), decreasing the side effect of long-run treatment protocols with highly efficient drugdrug activity.Method and results: Different samples were characterized by ATR-FTIR spectroscopy, X-ray diffraction, scanning electron microscopy coupled with energy dispersive X-ray analysis, transmission electron microscopy, thermogravimetric analysis, and dynamic light scattering along with cytotoxicity and anticancer study. A homogenous and compatible nanocomposite structure with a homogenous drug distribution was confirmed.Furthermore, the prepared nanocomposite has a low cytotoxicity effect against normal Vero cell lines compared with 5-FU. The antitumor activities of the same nanocomposite (20.4 and 74.3 μg mL −1 on A549 and HepG-2) were lower than that of 5-FU (54.1 and 103 μg mL −1 on A549 and HepG-2). Conclusion and implications:According to the attained results, the HPMC/5-FL@GO can apply in a biomedical application such as cancer therapy with the unique biocompatible to human cells.

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“…This improvement may refer to the stabilization effect of GO despite addition in a trace amount. [ 52 ]…”

Section: Resultsmentioning

confidence: 99%

“…This improvement may refer to the stabilization effect of GO despite addition in a trace amount. [52] On the other hand, the particle size distribution of GO, HPMC, and 5-FU are recorded as 706.3, 1562, and 916.6 nm, respectively.…”

Section: Dlsmentioning

confidence: 97%

Hydroxypropyl methylcellulose/graphene oxide composite as drug carrier system for 5‐fluorouracil

Hasanin

El-Sakhawy

Ahmed

et al. 2022

Biotechnology Journal

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“…However, the single components alone are not effective enough against corrosive media (acid, alkaline or neutral) and may have many drawbacks in the large-scale usage, where the solubility, as well as stability, would be of paramount interest 19 – 21 . Consequently, the use of polysaccharides composites is more required in the industry to obtain promising results 22 – 25 .…”

Section: Introductionmentioning

confidence: 99%

Green and sustainable chitosan–gum Arabic nanocomposites as efficient anticorrosive coatings for mild steel in saline media

Kiey

Hasanin²,

Heakal³

2022

Sci Rep

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The application of green and sustainable anticorrosive coatings is becoming of upsurge interest for the protection of metallic materials in aggressive environments. Herein, a stable crystalline chitosan/gum Arabic composite (CGAC) nanopowder was successfully synthesized and characterized by various methods. The CGAC nanopowder with different doses (25, 50, 100, and 200 ppm) was used to coat mild steel samples and examined its anticorrosion ability in 3.5 wt.% NaCl solution using gravimetric, electrochemical measurements, and surface characterization techniques. All methods yielded consistent results revealing that nanocomposite coatings can impart good anticorrosive properties to the steel substrate. The obtained protection efficiency was enhanced with increasing CGAC dose in the applied surface layer achieving 96.6% for the 200 ppm-coating. SEM and AFM surface morphologies of uncoated and coated samples after the inundation in the saline solution showed that CGAC coating can block the active corrosive sites on the steel surface, and prevent the aggressive Cl- ions from attacking the metallic substrate. The water droplet contact angle gave further support as it increased from 50.7° for the pristine uncoated surface to 101.2° for the coated one. The current research demonstrates a promising natural and reliable nanocomposite coating for protecting mild steel structures in the marine environment.

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“…In addition, the zeta potential measurements have affirmed respectively. [27,28] These results have confirmed the stability as well as homogeneity of StNPs in its aqueous solution.…”

Section: Dlsmentioning

confidence: 60%

Simple, Economic, Ecofriendly Method to Extract Starch Nanoparticles from Potato Peel Waste for Biological Applications

Hasanin

2021

Starch Stärke

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Nowadays, global strategies are focusing to decrease environmental waste loading that is developed with reuse or recycle waste products. Moreover, production of the high-value product from waste is desired especially if these wastes were previously of zero value. In the current work, a green and simple method for extraction of the high-value product (starch nanoparticles (StNPs)) from zero value waste (potato peel waste (PPW)) the accumulation of which harms the environment. Herein, a new simple method is carried out to prepare StNPs from PPW. The extraction of StNPs is carried out from PPW via simple alkali extraction followed by ultrasonic treatment. The produced StNPs are investigated using various analytical techniques. The antioxidant activity is assessed and shows promising results. In addition, the instrumental analyses confirm that the size of produced StNPs is about 50 nm with regular thin spherical shapes. The thermal stability is notable, as well as the amorphous structure in molecular level as well crystalline on the particle level. The DLS measurements affirm the high stability of StNPs in aqueous solution.

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Dielectric properties of nicotinic acid/methyl cellulose composite via “green” method for anti-static charge applications

Cited by 31 publications

References 40 publications

Hydroxypropyl methylcellulose/graphene oxide composite as drug carrier system for 5‐fluorouracil

Hydroxypropyl methylcellulose/graphene oxide composite as drug carrier system for 5‐fluorouracil

Green and sustainable chitosan–gum Arabic nanocomposites as efficient anticorrosive coatings for mild steel in saline media

Simple, Economic, Ecofriendly Method to Extract Starch Nanoparticles from Potato Peel Waste for Biological Applications

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