Dientamoeba fragilis Infection in Patients with Digestive and Non-Digestive Symptoms: A Case-Control Study

Hawash, Yousry; Ismail, Khadiga Ahmed; Saber, Taisir; Eed, Emad M.; Khalifa, Amany Salah; Alsharif, Khalaf F.; Alghamdi, Saleh A.

doi:10.3347/kjp.2020.58.2.129

Cited by 3 publications

(2 citation statements)

References 34 publications

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“…Diarrhoea, abdominal pain, constipation and urticarial findings were reported in symptomatic cases of Blastocystis infection (11)(12)(13). Similar to Blastocystis, non-specific GI symptoms including abdominal pain, cramps and diarrhoea were reported in symptomatic cases of D. fragilis (36). Nausea, vomiting, fever and eosinophilia have also been observed in cases with D. fragilis infection (2,37).…”

Section: Discussionmentioning

confidence: 93%

The high co-existence rate of Blastocystis and Dientamoeba fragilis in human faecal samples and the analysis of demographic and clinical findings

Malatyalı

Yıldız

Tileklioğlu

et al. 2021

Journal of Health Sciences and Medicine

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Aim: Blastocystis and Dientamoeba fragilis (D. fragilis) are among the most common protozoon species in human faecal samples. The cross-sectional studies have reported the frequencies in a variety of populations. However, we have very limited information about the co-existence rate of those protozoans. The study aimed to compare D. fragilis frequency in Blastocystis positive and negative faecal samples in order to determine the co-existence rate. The secondary objective was to analyse demographic characteristics and gastrointestinal (GI) symptoms in relation to both infections. Material and Method: In the present study, we defined a study group that included 100 Blastocystis positive faecal samples and a control group that included 100 Blastocystis negative samples. The frequency of D. fragilis in samples was determined with a PCR assay specific to the small-subunit ribosomal RNA (SS rRNA) gene. A positive control of D. fragilis was used and the samples with amplification of the expected size (863 bp) were considered as positive. In addition to the statistical comparison of frequencies, the descriptive and clinical findings of cases were analysed retrospectively with Pearson chi-square or ANOVA tests. Results: The frequency of D. fragilis was 21% in Blastocystis positive group and it was 10% in Blastocystis negative group. There was statistically significant difference in terms of D. fragilis positivity between the groups (p <0.05). Age, gender and GI symptoms did not reveal a significant difference between the following groups: only Blastocystis infected (n=77), only D. fragilis infected (n=11), infected with both protozoans (n=34) and non-infected individuals (n=89) (p >0.05). Conclusion:Our study highlighted the high co-existence of D. fragilis and Blastocystis in human faecal samples. A possible explanation for this finding may be the faecal-oral transmission of these protozoans. In addition, analysis of clinical findings was supported common asymptomatic colonisation of Blastocystis and D. fragilis.

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Section: Discussionmentioning

confidence: 93%

The high co-existence rate of Blastocystis and Dientamoeba fragilis in human faecal samples and the analysis of demographic and clinical findings

Malatyalı

Yıldız

Tileklioğlu

et al. 2021

Journal of Health Sciences and Medicine

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“…Other intestinal parasites such as Entamoeba histolytica, Entamoeba coli, Giardia sp., Blastocystis sp., Cryptosporidium sp., and Hymenolepis nana were detected. The most affected patients were in the age group ≤ 19 (Hawash et al 2020). In a study conducted among middle school boys in Jeddah in 2020, students were infected with Giardia lamblia, Blastocystis spp., Entamoeba histolytica, and helminths parasites (Ascaris lumbricoides, Trichuris trichiura, and Hymenolepis nana).…”

Section: Fig1 Percentages Of Parasites Present In Hail Patients Atmentioning

confidence: 99%

An overview of the most recent studies on the prevalence of intestinal parasites among Saudi society, with an emphasis on expatriate workers

Abbas,

Bakhraibah,

Al-Judaibi

2024

MBJ

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Parasite infection is a frequent ailment in many places across the world, particularly in developing nations. Intestinal parasites, which can be worms, infect the gastrointestinal tract and cause diseases, which spread through contaminated food or drink via the fecal-oral route. Parasitic infection is either symptomatic or asymptomatic in some infected patients. The economic boom led to a large influx of expatriate workers infected with intestinal parasites from endemic regions, particularly Asia and Africa. Therefore, their presence is a source of infection for the local population. This research presents what is known about previous studies related to intestinal parasites, different methods of diagnosis, types of intestinal parasites that were discovered among Saudis and expatriates in various regions of Saudi Arabia, and methods of treatment and prevention.

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The Coexistence of Blastocystis spp. in Humans, Animals and Environmental Sources from 2010–2021 in Asia

Rauff-Adedotun

Termizi

Shaari

et al. 2021

Biology

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Blastocystis spp. are controversial unicellular protists that inhabit the gastrointestinal tract of humans and a wide range of animals worldwide. This review provides an overview of the prevalence and distribution of Blastocystis spp. and their subtypes throughout Asia. Research articles reporting on the presence of Blastocystis spp. in locations within Asia, between 1 January 2010, and 10 May 2021, were obtained from Scopus, PubMed, and Google Scholar. In 427 articles, the prevalence of Blastocystis spp. in 31 countries within the last decade was revealed. Isolates were found in humans, various mammals, birds, reptiles, insects, water sources, vegetables, and ambient air. Prevalence of Blastocystis spp. varied widely across host categories. Subtypes identified throughout Asia were STs 1–14, and ST18–22 (novel subtypes). ST1, ST2, ST3, ST4 were the most frequently isolated in humans; ST5 in pigs; ST10 and ST14 in goats, sheep, and cattle; and ST6 and ST7 in chickens. ST1 and ST3 were most common in water samples. ST1, ST2, ST3, ST4, ST5 and ST6 were shared by humans, animals, and water sources. There is a growing interest in the study of Blastocystis spp. and their subtypes in Asia. Due to the isolation of Blastocystis spp. from biotic and abiotic sources in Asia, the application of the One Health (OH) approach to the study of Blastocystis spp. is proposed for improved perception of this organism.

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Dientamoeba fragilis Infection in Patients with Digestive and Non-Digestive Symptoms: A Case-Control Study

Cited by 3 publications

References 34 publications

The high co-existence rate of Blastocystis and Dientamoeba fragilis in human faecal samples and the analysis of demographic and clinical findings

The high co-existence rate of Blastocystis and Dientamoeba fragilis in human faecal samples and the analysis of demographic and clinical findings

An overview of the most recent studies on the prevalence of intestinal parasites among Saudi society, with an emphasis on expatriate workers

The Coexistence of Blastocystis spp. in Humans, Animals and Environmental Sources from 2010–2021 in Asia

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