Diet and Risk of Atrial Fibrillation - Epidemiologic and Clinical Evidence -

Gronroos, Noelle N.; Alonso, Álvaro

doi:10.1253/circj.cj-10-0820

Cited by 35 publications

(15 citation statements)

References 63 publications

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“…We did not separately assess risk of AF according to physical activity intensity, and these differences can not be excluded in this cohort as well. Similar to our study, prior literature has not demonstrated a reliable association between either total cholesterol or dietary components and AF 36, 37, 38, 39, 40, 41, 42. No previous studies have explored whether specific dietary patterns might be associated with the risk of AF.…”

Section: Discussionsupporting

confidence: 86%

American Heart Association's Life Simple 7 and Risk of Atrial Fibrillation in a Population Without Known Cardiovascular Disease: The ARIC (Atherosclerosis Risk in Communities) Study

Garg

O’Neal

Chen

et al. 2018

JAHA

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BackgroundThe American Heart Association has defined metrics of ideal cardiovascular health known as Life's Simple 7 (LS7) to prevent cardiovascular disease. We examined the association between LS7 and incident atrial fibrillation (AF) in a biracial cohort of middle‐ and older‐aged adults without known cardiovascular disease.Methods and ResultsThis analysis included 13 182 ARIC (Atherosclerosis Risk in Communities) study participants (mean baseline age=54±5.7 years; 56% women; 25% black) free of AF and cardiovascular disease. An overall LS7 score was calculated as the sum of the LS7 component scores and classified as inadequate (0‐4), average (5‐9), or optimal (10‐14) cardiovascular health. The primary outcome was incident AF, identified primarily by ECG and hospital discharge coding of AF through December 31, 2014. A total of 2266 (17%) incident AF cases were detected over a median follow‐up of 25.1 years. Compared with the inadequate category (n=1057), participants in the average (n=8629) and optimal (n=3496) categories each had a lower risk of developing AF in a multivariable Cox proportional hazards model (hazard ratio 0.59, 95% confidence interval 0.51, 0.67 for average; and hazard ratio 0.38, 95% confidence interval 0.32, 0.44 for optimal). In a similar model, a 1‐point‐higher LS7 score was associated with a 12% lower risk of incident AF (hazard ratio 0.88, 95% confidence interval 0.86, 0.89).ConclusionsA higher LS7 score is strongly associated with a lower risk of AF in individuals without baseline cardiovascular disease. Determining whether interventions that improve the population's cardiovascular health also reduce AF incidence is needed.

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Section: Discussionsupporting

confidence: 86%

American Heart Association's Life Simple 7 and Risk of Atrial Fibrillation in a Population Without Known Cardiovascular Disease: The ARIC (Atherosclerosis Risk in Communities) Study

Garg

O’Neal

Chen

et al. 2018

JAHA

Self Cite

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“…In most studies, we estimated caffeine exposure by coffee consumption which can lead to exposure misclassification bias. This would be expected to bias results towards the null (no association) [34]. Besides caffeine, coffee has other substances such as hypercholesterolemic compounds (cafestol and kahweol) [35], chlorogenic acid, flavonoids, melanoidins, compounds with antioxidant properties [36,37], and various lipid-soluble compounds such as furans, pyrroles, and maltol that may have either beneficial or harmful effect on the cardiovascular system [38].…”

Section: Limitationsmentioning

confidence: 99%

Does Caffeine Consumption Increase the Risk of New-Onset Atrial Fibrillation?

Abdelfattah

Kamran²,

Lazar³

et al. 2018

Cardiology

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Objective: Caffeine has been considered a trigger for atrial fibrillation (AF). We conducted a meta-analysis including a dose-response analysis to assess the relationship between caffeine consumed and incidence of AF. Methods: Data from selected studies represented 176,675 subjects (AF in 9,987 [5.7%]). Caffeine content varied widely, ranging from 40 to 180 mg per cup of coffee. For purposes of the calculations in this study, we assumed 140 mg of caffeine in a standard 12-oz cup of coffee. Results: No significant difference was found in AF incidence when the subjects consuming less than 2 cups of coffee per day were compared to subjects with higher consumption, 1.068 (0.937–1.216). The risk of AF was higher among subjects consuming less than 2 cups of coffee daily when compared to higher daily consumption subjects. A lower incidence of AF was found among people consuming more than 436 mg daily. Conclusion: The incidence of AF is not increased by coffee consumption. In fact, we found a lower incidence of AF when caffeine consumption exceeded 436 mg/day. Therefore, based on available evidence there is no association between caffeine intake and AF risk.

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“…83 There have been contrasting findings on the protective effect of specific kinds of fish on AF prevention. 84,85 Long-term, highly accurate monitoring of nutritional intake, or development of nutritional biomarkers, is essential for clarifying dietary contributions to AF risk.…”

Section: Epidemiologymentioning

confidence: 99%

Atrial Fibrillation

et al. 2011

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Atrial fibrillation (AF) is of public health importance and profoundly increases morbidity, mortality and health-related expenditures. Morbidities include the increased risks of cardiovascular outcomes such as heart failure and stroke, and the deleterious effects on quality of life, functional status and cognition. The clinical epidemiology of AF, its risk factors and outcomes, have been extensively investigated. Genetic advances over the last decade have facilitated the identification of mutations and common polymorphisms associated with AF. Metabolomics, proteomics and other “omics” technologies have only recently been applied to the study of AF, and have not yet been systematically investigated. Systems biology approaches, while still in their infancy, offer the promise of providing novel insights into pathways influencing AF risk. In the present review, we address the current state of the epidemiology and genomics of AF. We seek to emphasize how epidemiology and “omic” advances will contribute towards a systems biology approach that will help to unravel the pathogenesis, risk stratification, and novel targets for AF therapies. Our purpose is to articulate questions and challenges that hinge on integrating novel scientific advances in the epidemiology and genomics of AF. As a reference we have provided a glossary in the inset box.

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Diet and Risk of Atrial Fibrillation - Epidemiologic and Clinical Evidence -

Cited by 35 publications

References 63 publications

American Heart Association's Life Simple 7 and Risk of Atrial Fibrillation in a Population Without Known Cardiovascular Disease: The ARIC (Atherosclerosis Risk in Communities) Study

American Heart Association's Life Simple 7 and Risk of Atrial Fibrillation in a Population Without Known Cardiovascular Disease: The ARIC (Atherosclerosis Risk in Communities) Study

Does Caffeine Consumption Increase the Risk of New-Onset Atrial Fibrillation?

Atrial Fibrillation

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