Diet in the pathophysiology and management of irritable bowel syndrome

El-Salhy, Magdy

doi:10.3949/ccjm.83a.16019

Cited by 7 publications

(8 citation statements)

References 9 publications

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“…These carbohydrates are poorly digested or absorbed in the small intestine and can enter the colon, where they increase luminal osmotic pressure and induce gas production through fermentation of colonic bacteria, which can result in abdominal distension and pain [39–43]. Moreover, recent studies show that the byproducts of the interaction between FODMAPs and gut microbiota have an action on intestinal stem cells, resulting in an aberrant differentiation into endocrine cells and then leading to the development of visceral hypersensitivity, dysmotility, and abnormal intestinal secretion, all being features observed in IBS patients [44, 45].…”

Section: Discussionmentioning

confidence: 99%

The Role of Dietary Energy and Macronutrients Intake in Prevalence of Irritable Bowel Syndromes

Zhang

Zhu

et al. 2019

BioMed Research International

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Background. Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits in the absence of any detectable organic illnesses. Interest in the effect of dietary opponents to the IBS pathogenesis has been increased in recent years. This study aims to review previous studies to determine the relationship between IBS prevalence in community and dietary energy and macronutrients intakes according to the national nutrition surveys. Methods. A literature search was conducted in PubMed and EMBASE to September, 2018, to identify population-based studies that reported the prevalence of IBS. Daily energy intake, daily carbohydrates, and protein and fat percent contribution to energy intake (%) were obtained from study population-based national nutrition survey. The correlations of prevalence of IBS and dietary intakes were obtained by Spearman coefficient or Pearson coefficient. Results. Global prevalence of IBS was 11.7%. There was no correlation between overall prevalence of IBS of individual countries and national energy intake (P = 0.785), protein proportion (P = 0.063), carbohydrates proportion (P = 0.505), or fat proportion (P = 0.384) according to the years when the studies were conducted. No correlations were detected between dietary intake and male or female IBS prevalence. Interestingly, protein proportion was positively correlated with the prevalence of IBS in Rome III criteria (r = 0.569). Conclusion. Our findings demonstrate that dietary energy and macronutrients intake do not play a direct role in prevalence of IBS. However, IBS diagnostic criteria seem to have a bias on the correlation between prevalence of IBS and dietary intake. Further studies are needed to confirm the correlation between prevalence of IBS and specific dietary intake.

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Section: Discussionmentioning

confidence: 99%

The Role of Dietary Energy and Macronutrients Intake in Prevalence of Irritable Bowel Syndromes

Zhang

Zhu

et al. 2019

BioMed Research International

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“…However, the response rate among Asian IBS patients to the NICE-modified diet was 28%, compared to 41-54% in IBS patients in Europe and the USA [5][6][7]. This discrepancy could be explained by the patients randomized to the NICE-modified diet in the present study having received only brief dietary advice (5 min), compared to the structured dietary advice (30 min) provided to the low-FODMAP group, since structured dietary advice itself improves IBS symptoms [8][9][10]. Given the complexity of food dishes in Asia and the tradition of consuming up to six shared different dishes at each meal, recommending a low-FODMAP diet to Asian IBS patients is likely to be difficult.…”

Section: Role Of Diet In the Management Of Ibsmentioning

confidence: 62%

“…Furthermore, the treated patients received dietary guidance, whereas those in the control group did not. Dietary guidance has been reported to improve the symptoms and quality of life in IBS patients [8][9][10], and so it is not clear whether the effect of a low-starch, low-sucrose diet is due to the intervention or the placebo effect added to the effect of the provided dietary information. Further double-blind placebo-controlled studies are needed before any definite conclusion can be drawn.…”

Section: Role Of Diet In the Management Of Ibsmentioning

confidence: 99%

Nutritional Management of Gastrointestinal Diseases and Disorders

El-Salhy

2019

Nutrients

Self Cite

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“…FODMAPs can pass unabsorbed to the colon, where they increase luminal water through osmotic activity and induce gas production due to fermentation by colonic bacteria, which can result in luminal distension and GI symptoms in patients with IBS[74-77]. Moreover, recent studies show that the by-products of the interaction between FODMAPs and gut microbiota act on intestinal stem cells, resulting in aberrant differentiation of these cells into endocrine cells and leading to an abnormal density of endocrine cells in the gut[78]. GI endocrine cells regulate GI sensitivity, motility, secretion, absorption, local immune defense, and appetite[47].…”

Section: Second-line Dietary Approach In Ibs: the Low Foodmap Dietmentioning

confidence: 99%

“…GI endocrine cells regulate GI sensitivity, motility, secretion, absorption, local immune defense, and appetite[47]. Therefore, abnormalities in the GI endocrine cells may play a major role in the development of visceral hypersensitivity, dysmotility, and abnormal intestinal secretion, all being features observed in patients with IBS[47,78]. …”

Section: Second-line Dietary Approach In Ibs: the Low Foodmap Dietmentioning

confidence: 99%

Diet in irritable bowel syndrome: What to recommend, not what to forbid to patients!

Cozma-Petruț

Loghin

Miere

et al. 2017

WJG

121

131

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A substantial proportion of patients with irritable bowel syndrome (IBS) associate their symptoms with the ingestion of specific foods. Therefore, in recent years, scientific research has increasingly focused on the role of diet in IBS and dietary management is now considered an important tool in IBS treatment. This article reviews the main dietary approaches in IBS emphasizing evidence from experimental and observational studies and summarizing the main diet and lifestyle recommendations provided by dietary guidelines and scientific literature. Despite the limited evidence for a beneficial role, general advice on healthy eating and lifestyle is recommended as the first-line approach in the dietary management of IBS. Standard recommendations include adhering to a regular meal pattern, reducing intake of insoluble fibers, alcohol, caffeine, spicy foods, and fat, as well as performing regular physical activity and ensuring a good hydration. Second-line dietary approach should be considered where IBS symptoms persist and recommendations include following a low FODMAP diet, to be delivered only by a healthcare professional with expertise in dietary management. The efficacy of this diet is supported by a growing body of evidence. In contrast, the role of lactose or gluten dietary restriction in the treatment of IBS remains subject to ongoing research with a lack of high-quality evidence. Likewise, further clinical trials are needed to conclude the efficacy of probiotics on IBS symptoms.

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Diet in the pathophysiology and management of irritable bowel syndrome

Cited by 7 publications

References 9 publications

The Role of Dietary Energy and Macronutrients Intake in Prevalence of Irritable Bowel Syndromes

The Role of Dietary Energy and Macronutrients Intake in Prevalence of Irritable Bowel Syndromes

Nutritional Management of Gastrointestinal Diseases and Disorders

Diet in irritable bowel syndrome: What to recommend, not what to forbid to patients!

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