Diet soft drink is associated with increased odds of proliferative diabetic retinopathy

Fenwick, Eva; Gan, Alfred Tl; Sabanayagam, Charumathi; Gupta, Preeti; Khoo, Krystal; Aravindhan, Amudha; Wong, Tien Yin; Lamoureux, Ecosse L.

doi:10.1111/ceo.13154

Cited by 6 publications

(13 citation statements)

References 44 publications

(84 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reverse holds for non-caloric flavor consumption (associated with obesity only). Our findings are in line with a previous study conducted among 609 patients with diabetes 14 and found a two-fold increase in proliferative DR among those who consumed >4 bottles/week. Further previous studies reported the association of diet soda and artificial sweeteners with a high body mass index and cardiometabolic consequences.…”

Section: Discussionsupporting

confidence: 93%

“…Soft drink consumption: depend on validity and reproducibility of a 145-item self-administered food frequency questionnaire (FFQ), and according to it all patients sample were asked about consumption of soft drink then divided to no consumption when using less than 1 can/week (375mL), moderate when using 1–4 cans/week, severe when using more than 5 cans/week. 13 , 14 …”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Diet Sugar-Free Carbonated Soda Beverage, Non-Caloric Flavors Consumption, and Diabetic Retinopathy: Any Linkage

Mirghani

Alali

ALBalawi

et al. 2021

DMSO

View full text Add to dashboard Cite

Purpose: Assessing diabetic retinopathy (DR) risk factors and daily nutrition habits are vital for prevention. This study aims to evaluate the relationship between diet soda cans, nonnutritive sweetener consumption, and diabetic retinopathy. Patients and Methods: A cross-sectional study was conducted among 200 patients attending a diabetes center in Tabuk City, Saudi Arabia, from September 2019 to July 2020. A structured questionnaire was used to collect patients' demographic factors, and DR risk factors including the use of diet soda, non-nutritive sweeteners, and exercise habits. Dilated fundus eye examination was done to detect any diabetic retinopathy. A blood sample was taken for measuring glycated hemoglobin to assess the degree of glycemic control. Results: The participant's age was 50.74 ±13.51 years, and the duration since the diagnosis of diabetes was 9.99 ±6.97 years, body mass index was 27.28 ±4.68, and HbA1c %, 8.50 ±1.61), the patients used to consume 1.31 ±1.57 diet soda cans/week, and 1.06±1.39 artificial sweeteners/sachet/day. DR was found in 33%. Diet sugar-free carbonated soda beverage was associated with poor glycemic control and retinopathy, while non-caloric flavor consumption was associated with obesity (P-value<0.05). No association was evident regarding other factors (P-value>0.05). Conclusion: Diet sugar-free carbonated soda beverage was associated with higher HbA1c and retinopathy, while non-caloric flavor consumption was associated with obesity. No association was evident regarding other factors. Further larger multicenter studies are needed.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Methodsmentioning

confidence: 99%

Diet Sugar-Free Carbonated Soda Beverage, Non-Caloric Flavors Consumption, and Diabetic Retinopathy: Any Linkage

Mirghani

Alali

ALBalawi

et al. 2021

DMSO

View full text Add to dashboard Cite

show abstract

“…In addition, a meta-analyses of 11 cohorts reported that after adjustment for age, gender, energy intake, BMI, and other dietary covariates, each additional serving of sugar-sweetened beverage was associated with higher fasting glucose ( β ± SE 0.014±0.004 [mmol/L]; P =1.5×10 –3 ) and higher fasting insulin (0.030±0.005 [log e pmol/L]; P =2.0×10 –10 ) 30. Furthermore, literature on the consumption of fizzy drinks reports that they increase the risk of diabetic complications, ie, chronic kidney disease and proliferative diabetic retinopathy 31,32…”

Section: Discussionmentioning

confidence: 99%

<p>Impact of food pattern on glycemic control among type 2 diabetic patients: a cross-sectional study in the United Arab Emirates</p>

Sadiya¹,

Mnla²

2019

DMSO

View full text Add to dashboard Cite

Background Optimum nutrition has an integral role in glycemic control of diabetic patients. In this study, we intend to explore the frequency of food group/item consumption and its association with the risk of poor glycemic control (Hb A1c >7%) among type 2 diabetes (T2D) patients in the United Arab Emirates (UAE), since there are no data available in this region. Methods In this retrospective cross-sectional study, data on frequency of food group/item consumption of 843 T2D patients aged ≥18 years were collected from records documented by dietitians in a tertiary care center in the UAE. Results The trends of food consumption demonstrate that one-third of the participants consumed all five major food groups, and 10% adhered to the recommended “MyPlate” meal pattern with the optimum mix of food groups. Univariate analysis indicated that participants who adhered to the MyPlate meal pattern presented lower Hb A1c ( β =−0.78, 95% CI −1.22, −0.25; P <0.01). Daily intake of fresh fruit was shown to be protective ( β =−0.64, 95% CI −1.26, −0.04; P =0.04) while fruit juice intake >1 time/day increased the risk of poor glycemic control ( β =1.53, 95% CI 0.72, 2.35; P <0.001). Multiple logistic regression models (area under the receiver operating characteristics curve =0.67) showed consumption of fizzy drinks and fast food ≥1 time/week increased the odds of poor glycemic control by 2.05 (95% CI 1.16, 3.68; P =0.01) and 1.83 (95% CI 1.02, 3.3 P =0.04), respectively, while fresh fruit consumption indicated a clinically relevant protective effect (OR=0.65, 95% CI 0.23, 1.79; P =0.4). Conclusion Consuming food such as fizzy drinks and fast food ≥1 time/week could possibly serve as an independent predictor for poor glycemic control, while fresh fruit could have a protective effect on glycemic control among T2D patients. Clinical Trial Registry: ClinicalTrials.gov Identifier: NCT03388229

show abstract

“…The growing popularity of diet soft drinks in recent years has been driven by increasing recognition of the adverse health consequences of sugar consumption and, in particular, the potential harms of sugar-sweetened soft drinks. 4 The cross-sectional study of 609 people with diabetes (87.5% type 2 diabetes) investigated the association between soft drink consumption and diabetic retinopathy (DR). 'Regret nothing no sugar, no calories' is a recent marketing catchphrase of a leading diet soft drink.…”

mentioning

confidence: 99%

“…2,3 An interesting study by Fenwick et al, in this edition of the Journal, highlights the potential harm of diet soft drink consumption in people with diabetes. 4 The cross-sectional study of 609 people with diabetes (87.5% type 2 diabetes) investigated the association between soft drink consumption and diabetic retinopathy (DR). Individuals who consumed more than four cans of diet soft drink per week (heavy consumption) had more than a two-fold increased likelihood of having proliferative DR (OR = 2.62) than those who did not.…”

mentioning

confidence: 99%

More than meets the eye: an association between diet soft drink consumption and proliferative diabetic retinopathy

Wijngaarden

Keel

2018

Clinical Exper Ophthalmology

View full text Add to dashboard Cite

show abstract

Diet soft drink is associated with increased odds of proliferative diabetic retinopathy

Cited by 6 publications

References 44 publications

Diet Sugar-Free Carbonated Soda Beverage, Non-Caloric Flavors Consumption, and Diabetic Retinopathy: Any Linkage

Diet Sugar-Free Carbonated Soda Beverage, Non-Caloric Flavors Consumption, and Diabetic Retinopathy: Any Linkage

<p>Impact of food pattern on glycemic control among type 2 diabetic patients: a cross-sectional study in the United Arab Emirates</p>

More than meets the eye: an association between diet soft drink consumption and proliferative diabetic retinopathy

Contact Info

Product

Resources

About