Dietary and Lifestyle Factors Associated with Gastric and Pancreatic Cancers: A Case-Control Study

Al-Awwad, Narmeen J.; Allehdan, Sabika; Al‐Jaberi, Tareq; Hushki, Ahmad; Albtoush, Yazan; Bani-Hani, Kamal E.; Tayyem, Reema

doi:10.3746/pnf.2021.26.1.30

Cited by 11 publications

(9 citation statements)

References 22 publications

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“…Table 2 shows the characteristics of participants with GC (n = 172) and PC (n = 101) and controls (n = 314) as have been described by Al-Awwad et al [18] study. Participants with PC had similar age, height, and in-come as controls.…”

Section: Resultsmentioning

confidence: 99%

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Dietary patterns associated with the risk of pancreatic cancer: Case-control study findings

et al. 2022

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Diet is an important modifiable lifestyle factor, but epidemiological studies evaluating the association between dietary patterns and pancreatic cancer (PC) have reported inconsistent findings. This study aimed to evaluate the impact of several dietary choices on the risk of PC among newly diagnosed Jordanian patients. A case-control study was conducted at major teaching and general hospitals, including a Jordanian oncology center. The study included 101 patients with incident pancreatic cancer and 314 controls. Data was collected using interview-based questionnaires. Dietary intake was estimated using a validated Arabic and reproducible food-frequency questionnaire. Dietary patterns were derived using Principal Component Analysis. Multinomial logistic regression was used to estimate the association between dietary patterns and PC. Four dietary patterns were identified. The "Traditional" dietary pattern, which presented a diet rich in fresh fruits, vegetables, milk, yogurt, and lentils, was associated with a significant decrease in the odds of PC (OR = 0.42, 95% CI = 0.21-0.84) for the third quartile compared to first one. The "High-fruit" dietary pattern, which was loaded with strawberry, melon, watermelon, and other fruits, significantly reduced the odds of PC (OR = 0.38, 95% CI = 0.19-0.75) for the second quartile compared to the first one. The "Soup" dietary pattern was mainly composed of vermicelli soup, vegetable soup, lentil soup, and mushroom soup, which decreased the odds of PC (OR = 0.18, 95% CI = 0.07-0.38). There was no relation between PC and the "Western" dietary pattern, loaded with beer, wine, roasted lamb, meat, chicken sandwich, beefsteak, and fried fish. The "Traditional," "High-fruit," and "Soup" dietary patterns were associated with reduced risk of PC among Jordanians.Abbreviations: BMI = body mass index, CI = confidence interval, FFQ = food frequency questionnaire, KHCC = King Hussein Cancer Center's, KMO = Kaiser-Meyer-Olkin, MET = metabolic equivalents, OR = odds ratios, PAR = seven-day physical activity recall, PC = pancreatic cancer, PCA = Principal Component Analysis.

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Section: Resultsmentioning

confidence: 99%

“…Potential confounders (adjusted for age, gender, BMI, smoking, marital status, total energy intake, education level, and physical activity) were chosen based on reported risk factors for PC. [17,18] Odds ratios (OR) and 95% confidence interval (CI) were calculated using a multinomial logistic regression model.…”

Section: Methodsmentioning

confidence: 99%

Dietary patterns associated with the risk of pancreatic cancer: Case-control study findings

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“…Odds ratios (ORs) and 95% confidence intervals (95% CIs) for GC were calculated using a multinomial logistic regression mode according to tertile of energy and energy adjusted macronutrient intakes, with the lowest tertile as the reference group. Potential confounders (age, gender, marital status, education, BMI, smoking, period of smoking, family history of gastric cancer, presence of gastric ulcer, and physical activity (MET-min/week)) were selected based on reported risk factors for GC in previous studies [36,43,44]. p-value for trend was calculated using linear logistic regression model.…”

Section: Discussionmentioning

confidence: 99%

Macronutrients Intake and Risk of Stomach Cancer: Findings from Case-Control Study

et al. 2022

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Studies on the association between gastric cancer (GC) and the intake of nutrients in Jordan are very limited, while findings from other reports on the intake of energy and macronutrients are controversial. This study aimed to examine the associations between intake of energy and macronutrients and the risk of GC in a Jordanian population. A case-control study was carried out between March 2015 and August 2018 in four major hospitals, including an oncology center in Jordan. Study participants were 173 cases with incident and histologically confirmed GC and 314 frequency-matched controls. Interview-based questionnaires were used to obtain the study’s information. Data on nutrient intake were collected using a validated Arabic food-frequency questionnaire (FFQ). Odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) were calculated through multinomial logistic regression and adjusted for potential confounders, including age, marital status, education, body mass index (BMI), smoking, period of smoking, family history of gastric cancer, history of gastric ulcer, and physical activity. Intakes of total fat, saturated fat, monounsaturated fat, polyunsaturated fat, cholesterol, trans-fat, and omega-6 fatty acids were significantly associated with increased risk of GC. The ORs for the highest versus the lowest tertiles were 6.47 (95% Cl: 3.29–12.77), 2.97 (95% CI: 1.58–5.58), 6.84 (95% CI: 3.46–13.52), 6.19 (95% CI: 3.15–12.17), 3.05 (95% CI: 1.58–5.88), 8.11 (95% CI: 4.20–15.69), and 2.74 (95% CI: 1.47–5.09), respectively. No significant association was found for energy, protein, carbohydrate, sugar, fibers, and omega-3 fatty acids. The findings of this study suggest that high intake of selected types of fats was associated with an increased risk of GC.

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“…The primary preventative measures are a healthy diet, H. pylori treatments, chemoprevention, and early detection testing. Dietary factors have a substantial impact on the development of stomach cancer [5]. Sporadic gastric cancer, early-onset gastric cancer, gastric stump cancer, and hereditary diffuse gastric cancer are the four types of stomach cancer (HDGC).…”

Section: Gastric Cancermentioning

confidence: 99%

Role of Probiotics in the Prevention and Treatment of GIT Cancers: Updated Review

Hassan¹,

Hasary

Hassan

2023

Al-Rafidain J Med Sci

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Cancer, one of the leading causes of death worldwide, has been the subject of extensive study by many researchers. Cancer is affected by both genetic and immune system factors in the human body. The gut microbiota plays an important role in the body's capacity to maintain homeostasis. Because of their beneficial effects on human health and their ability to successfully prevent and treat various chronic diseases, such as cancer, probiotics are becoming increasingly important in medicine. A wealth of research has shown that probiotic consumption can significantly helpful in cancer prevention and treatment. The goal of this review is to provide a thorough overview of the research on the function of probiotic bacteria in the prevention and treatment of gastrointestinal cancers.

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Dietary and Lifestyle Factors Associated with Gastric and Pancreatic Cancers: A Case-Control Study

Cited by 11 publications

References 22 publications

Dietary patterns associated with the risk of pancreatic cancer: Case-control study findings

Dietary patterns associated with the risk of pancreatic cancer: Case-control study findings

Macronutrients Intake and Risk of Stomach Cancer: Findings from Case-Control Study

Role of Probiotics in the Prevention and Treatment of GIT Cancers: Updated Review

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