Dietary Inflammatory Index Score and Cardiovascular Disease Risk Markers in Women with Systemic Lupus Erythematosus

Pocovi-Gerardino, Gabriela; Correa‐Rodríguez, María; Callejas‐Rubio, José Luis; Ríos-Fernández, Raquel; Martín-Amada, María; Cruz-Caparrós, María-Gracia; Rueda‐Medina, Blanca; Ortego-Centeno, Norbérto

doi:10.1016/j.jand.2019.06.007

Cited by 19 publications

(17 citation statements)

References 42 publications

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“…105 In a study of 105 Spanish women with systemic lupus erythematosus, which poses an increased risk of CVD due to its inflammatory nature, there was a positive relationship between DII and total cholesterol but no other CVD-RFs (HDL-cholesterol, LDLcholesterol, triglycerides, high-sensitivity CRP, and homocysteine levels). 119 In a cross-sectional study of 266 Iranian women with overweight or obesity, DII scores were significantly associated with lower HDL and higher triglyceride levels. 78 In the abovementioned Cork and Kerry Diabetes and Heart Disease Study of 1992 adults (49% male), E-DII above the median was associated with 2 mmHg increase in SBP but not DBP as well as small but significant changes in LDLcholesterol, HDL-cholesterol, and triglyceride levels.…”

Section: Cross-sectional Studiesmentioning

confidence: 99%

The dietary inflammatory index, obesity, type 2 diabetes, and cardiovascular risk factors and diseases

et al. 2021

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SummaryAn unhealthy diet is a recognized risk factor in the pathophysiology of numerous chronic noncommunicable diseases (NCD), including obesity, type 2 diabetes (T2DM), and cardiovascular diseases (CVD). This is, at least in part, due to unhealthy diets causing chronic low‐grade inflammation in the gut and systemically. To characterize the inflammatory potential of diet, we developed the Dietary Inflammatory Index (DII®). Following this development, around 500 papers have been published, which examined the association between the DII, energy‐adjusted DII (E‐DII™), and the children's DII (C‐DII™) and many chronic NCDs including obesity and cardiometabolic diseases. Although a previous narrative review published in 2019 briefly summarized the evidence in this area, there was a significant increase in papers on this topic since 2020. Therefore, the purpose of this narrative review is to provide an in‐depth updated review by including all papers until July 2021 on DII and its relationship with obesity, T2DM, and CVD. Furthermore, we aim to identify potential gaps in the literature and provide future directions for research. Most studies found that DII was associated with an increased risk of obesity, T2DM, and CVD with some relationships being sex‐specific. However, we identified the paucity of papers describing associations between dietary inflammation and T2DM and its risk factors. Few studies used gold‐standard measures of cardiometabolic risk factors. We also identified the lack of interventional studies designed to change the inflammatory potential of diets and study its effect on cardiometabolic risk factors and diseases. We recommend that such interventional studies are needed to assess if changes in DII, representing the inflammatory potential of diet, independently of changes in body composition can modulate cardiometabolic risk factors and diseases.

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Section: Cross-sectional Studiesmentioning

confidence: 99%

The dietary inflammatory index, obesity, type 2 diabetes, and cardiovascular risk factors and diseases

et al. 2021

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“…Only two studies addressed the role of fatty acids in patients with SLE. In a cross-sectional study on women with SLE ( n = 105), a diet with inflammatory potential (measured here as high dietary inflammatory index) was associated with a less-favorable lipid profile in patients with SLE ( 80 ). A population-based study ( n = 456) suggested that a higher dietary intake of ω-3 fatty acids and lower ω-6:ω-3 ratios were favorably associated with self-reported lupus activity and sleep quality ( 81 ).…”

Section: Macronutrientsmentioning

confidence: 99%

Immunomodulatory Effects of Diet and Nutrients in Systemic Lupus Erythematosus (SLE): A Systematic Review

et al. 2020

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Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple organ involvement, including the skin, joints, kidneys, lungs, central nervous system and the haematopoietic system, with a large number of complications. Despite years of study, the etiology of SLE remains unclear; thus, safe and specifically targeted therapies are lacking. In the last 20 years, researchers have explored the potential of nutritional factors on SLE and have suggested complementary treatment options through diet. This study systematically reviews and evaluates the clinical and preclinical scientific evidence of diet and dietary supplementation that either alleviate or exacerbate the symptoms of SLE. For this review, a systematic literature search was conducted using PubMed, Scopus and Google Scholar databases only for articles written in the English language. Based on the currently published literature, it was observed that a low-calorie and low-protein diet with high contents of fiber, polyunsaturated fatty acids, vitamins, minerals and polyphenols contain sufficient potential macronutrients and micronutrients to regulate the activity of the overall disease by modulating the inflammation and immune functions of SLE.

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“…The results showed no a significant correlation between DIP and CVD in females while a significant relationship was found in male subjects [42]. Similarly, Gabriela Pocovi-Gerardino et al conducted a cross-sectional study on 105 women with a mean age of 45.4 years old and found no significant correlation between the DIP score and CVD markers [43]. A study of 585 women aged 50-55 years old by Linda E. T. Vissers et al failed to show any correlation between DIP and CVD, ischemic heart disease, and myocardial infarction (MI) [44].…”

Section: Discussionmentioning

confidence: 93%

Association of dietary inflammatory potential (DIP) and endothelial function biomarkers among female nurses of Isfahan hospitals

Gholizadeh

Falahi²,

Keshteli³

et al. 2021

Preprint

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Background Dietary inflammatory index (DIP) is a new dietary index designed to evaluate individuals’ diets. In addition, adhesion molecules are important biomarkers for assessing endothelium inflammation that they related to atherosclerosis and cardiovascular disease. Also, there is no study for assessing the association between adhesion molecules and DIP until now as well as other studies that assessed the relationship between dietary inflammatory index or DIP have controversy. Aim of the Work The purpose of this cross-sectional study was to determine the correlation between DII and endothelial markers such as E-selectin, intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) among female nurses from Isfahan. In this study, dietary inflammatory potential (DIP) was used instead of DII. Patients and Methods This study was performed on 420 healthy nurses. The nurses were selected by random cluster sampling method from private and public Isfahan hospitals. A validated food frequency questionnaire (FFQ) was applied to assess the dietary inflammatory potential. A fasting blood sample was collected for measuring the plasma levels of the endothelial markers and other variables. Results After adjusting different potential confounders, no statistical association was found between DIP and sICAM-1, E–selectin and sVCAM-1 in model I (P=0.57, 0.98 and 0.45), model II (P=0.57, 0.98 and 0.45) and model III (P=0.67, 0.92 and 0.50) in comparison to the crude group (P=0.35, 0.83 and 0.49, respectively). Conclusion The results revealed that the plasma levels of endothelial markers including E-selectin, sICAM-1, and sVCAM-1 were not significantly associated with DIP in female nurses.

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Dietary Inflammatory Index Score and Cardiovascular Disease Risk Markers in Women with Systemic Lupus Erythematosus

Cited by 19 publications

References 42 publications

The dietary inflammatory index, obesity, type 2 diabetes, and cardiovascular risk factors and diseases

The dietary inflammatory index, obesity, type 2 diabetes, and cardiovascular risk factors and diseases

Immunomodulatory Effects of Diet and Nutrients in Systemic Lupus Erythematosus (SLE): A Systematic Review

Association of dietary inflammatory potential (DIP) and endothelial function biomarkers among female nurses of Isfahan hospitals

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