Dietary intakes and lifestyle patterns of Korean children and adolescents with atopic dermatitis: Using the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV,V), 2007–11

Yang, Ae-Ri; Kim, Young Nam; Lee, Bog‐Hieu

doi:10.1080/03670244.2015.1072813

Cited by 12 publications

(6 citation statements)

References 29 publications

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“…Also, in large population-based studies, it was observed that there is an increased likelihood of developing AD in individuals with either deficient or insufficient vitamin D levels [117,118]. Many observational studies including a meta-analysis have shown that the serum vitamin D level is lower in children and adults with AD compared to controls, and reported an association between vitamin D deficiency and risk of atopic eczema [119,120,121]. Also, the severity of AD was found to be negatively correlated with the vitamin D level, with moderate and severe AD groups having lower vitamin D levels compared to the mild AD group; this finding was supported by the use of objective tools, such as the SCORAD (Scoring Atopic Dermatitis) index, which was found to be inversely correlated with vitamin D levels in AD patients [120,121,122,123].…”

Section: Role Of Vitamin D In Certain Inflammatory Skin Diseasesmentioning

confidence: 99%

Vitamin D and the Pathophysiology of Inflammatory Skin Diseases

Umar

Sastry

Ali

et al. 2018

Skin Pharmacol Physiol

149

135

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Background: Vitamin D is a secosteroid, which was initially known for its skeletal role; however, in recent years, its functions in different organs have been increasingly recognized. In this review, we will provide an overview of vitamin D functions in the skin physiology with specific focus on its role in certain inflammatory skin conditions such as psoriasis and atopic dermatitis. Methods: A comprehensive literature search was carried out in PubMed and Google Scholar databases using keywords like “vitamin D,” “skin,” “atopic dermatitis,” and “psoriasis.” Only articles published in English and related to the study topic were included in this review. Results: Vitamin D is integrally connected to the skin for its synthesis, metabolism, and activity. It regulates many physiological processes in the skin ranging from cellular proliferation, differentiation, and apoptosis to barrier maintenance and immune functions. Vitamin D deficiency is associated with the risk of psoriasis and atopic dermatitis, and several clinical/observational studies have suggested the beneficial effect of vitamin D in the therapy of these 2 inflammatory skin disorders. Conclusions: Vitamin D exerts a pleiotropic effect in the skin and could be an important therapeutic option for psoriasis and atopic dermatitis.

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Section: Role Of Vitamin D In Certain Inflammatory Skin Diseasesmentioning

confidence: 99%

Vitamin D and the Pathophysiology of Inflammatory Skin Diseases

Umar

Sastry

Ali

et al. 2018

Skin Pharmacol Physiol

149

135

View full text Add to dashboard Cite

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“…Vitamin D also plays a vital role in the development of certain inflammatory skin diseases. Many observational studies, including a meta-analysis, have found that levels of serum vitamin D are lower in adults and children with atopic dermatitis (AD) than in controls and that vitamin D insufficiency is linked to the risk of atopic eczema [61][62][63]. Many investigations have found a shortage or insufficiency of serum vitamin D in psoriatic patients, indicating that vitamin D plays an important role in the disease [64,65].…”

Section: Role Of Vitamin Dmentioning

confidence: 99%

Influence of Ethnicities and Skin Color Variations in Different Populations: A Review

Naik

Farrukh

2021

Skin Pharmacol Physiol

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Background: In the world scientific tradition, skin color is the primary physical characteristic used to divide humans into groups. Human skin has a wide range of tones and colors, which can be seen in a wide range of demographic populations. Many factors influence the color of people’s skin, but the pigment melanin is by far the most important. Melanin is produced by cells called melanocytes in the skin and is the primary determinant of skin color in people with darker skin. Indeed, >150 genes have now been identified as having a direct or indirect effect on skin color. Vitamin D has recently been discovered to regulate cellular proliferation and differentiation in a variety of tissues, including the skin. The mechanisms through which the active vitamin D metabolite 1,25 dihydroxyvitamin D3 (or calcitriol) affects keratinocyte development are numerous and overlap with the mechanisms by which calcium influences keratinocyte differentiation. Ultraviolet (UV) is the most major modifiable risk factor for skin cancer and many other environmental-influenced skin disorders when it is abundant in the environment. Although the UV component of sunlight is known to cause skin damage, few researches have looked at the impact of non-UV solar radiation on skin physiology in terms of inflammation, and there is less information on the role of visible light in pigmentation. Summary: The quantity and quality of melanin are regulating by the expression of genes. The enzyme tyrosinase is primarily responsible for the genetic mechanism that controls human skin color. Genetics determines constitutive skin color, which is reinforced by facultative melanogenesis and tanning reactions. High quantities of melanin and melanogenic substances are typically accepted in darker skin to protect against UV radiation-induced molecular damage. Previous research has proposed that skin color variation is caused by a dynamic genetic mechanism, contributing to our understanding of how population demographic history and natural selection shape human genetic and phenotypic diversity. However, the most significant ethnic skin color difference is determined by melanin content. This current review aimed to assess the influence of skin color variations in skin structure and functions as well as difference in dermatological disease patterns. Also, this article reviewed several cases of skin color adaptation in different populations. Key Messages: Skin color impacts the composition and activity. Therefore, the contrast of dermatological ailments between distinct race-related categories is remarkable. Skin color adaptation is a challenging procedure. Refinement of skin color is an age-old craving of humans with ever-evolving drifts.

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“…Furthermore, vitamin D treatment can dampen the enhanced IgE response in AD by lowering the IgE production by human B cells and suppressing IgE-mediated mast cell activation [ 238 ]. Many case-control studies have shown a lower level of vitamin D in AD subjects compared to controls and the association of vitamin D deficiency to a more severe course of the disease [ 239 , 240 , 241 ]. In a prospective cohort study, it was observed that vitamin D-deficient individuals have an increased likelihood of developing AD [ 242 ].…”

Section: Molecular and Clinical Studies Of Vitamin D In Various Dimentioning

confidence: 99%

Role of Vitamin D Beyond the Skeletal Function: A Review of the Molecular and Clinical Studies

Umar

Sastry

Chouchane

2018

IJMS

201

151

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The classical function of Vitamin D, which involves mineral balance and skeletal maintenance, has been known for many years. With the discovery of vitamin D receptors in various tissues, several other biological functions of vitamin D are increasingly recognized and its role in many human diseases like cancer, diabetes, hypertension, cardiovascular, and autoimmune and dermatological diseases is being extensively explored. The non-classical function of vitamin D involves regulation of cellular proliferation, differentiation, apoptosis, and innate and adaptive immunity. In this review, we discuss and summarize the latest findings on the non-classical functions of vitamin D at the cellular/molecular level and its role in complex human diseases.

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Dietary intakes and lifestyle patterns of Korean children and adolescents with atopic dermatitis: Using the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV,V), 2007–11

Cited by 12 publications

References 29 publications

Vitamin D and the Pathophysiology of Inflammatory Skin Diseases

Vitamin D and the Pathophysiology of Inflammatory Skin Diseases

Influence of Ethnicities and Skin Color Variations in Different Populations: A Review

Role of Vitamin D Beyond the Skeletal Function: A Review of the Molecular and Clinical Studies

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