Dietary interventions for rheumatoid arthritis

Hagen, Kåre Birger; Byfuglien, Marte Gjeitung; Falzon, Louise; Olsen, Sissel Urke; Smedslund, Geir

doi:10.1002/14651858.cd006400.pub2

Cited by 94 publications

(58 citation statements)

References 39 publications

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“…Unfortunately there is a dearth of robust evidence in human participants, with very few good-quality trials completed on diet supplementation to treat patients with chronic painful symptoms. 53,54 Pre-clinical findings suggest that dietary omega-3/ omega-6 ratio may have significance for inflammatory pain. Increasing omega-3 intake (found in fish) reduced patient-reported joint pain intensity, morning stiffness and the number of painful joints in patients with rheumatoid arthritis or joint pain secondary to inflammatory bowel disease.…”

Section: Sleep Problemsmentioning

confidence: 99%

Chronic pain epidemiology – where do lifestyle factors fit in?

Hecke

Torrance

Smith

2013

British Journal of Pain

154

104

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Chronic pain is common and complex and has a large impact on individuals and society. Good epidemiological pain data provide key information on the use of resources (both in general practice and in specialist clinics), insight into factors that lead to or favour chronicity and the design of interventions aimed at reducing or preventing the effects of chronic pain. This review aims to highlight the important factors associated with chronic pain, including those factors which are amenable to lifestyle intervention.

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Section: Sleep Problemsmentioning

confidence: 99%

Chronic pain epidemiology – where do lifestyle factors fit in?

Hecke

Torrance

Smith

2013

British Journal of Pain

154

104

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“…In particular, there is evidence that a medical short-time fasting followed by a Mediterranean diet can reduce key symptoms of RA [5].…”

Section: Introductionmentioning

confidence: 99%

“…Due to the clinical benefits observed in patients with RA during fasting or a Mediterranean diet [5,6] and due to the alterations of SCFA from the intestinal microflora during dietary interventions [10,17], we aimed to analyse the whole who had consented to participate in the study, regardless whether or not they gave a full set of data or adhered to the protocol. Missing values were replaced by carrying forward the last available observation.…”

Section: Introductionmentioning

confidence: 99%

Changes of Intestinal Microflora in Patients with Rheumatoid Arthritis during Fasting or a Mediterranean Diet

Abendroth

Michalsen²,

Lüdtke³

et al. 2010

Forsch Komplementmed

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Background: Therapeutic dietary interventions are effective treatments for rheumatoid arthritis (RA). The mechanisms to affect inflammation and clinical outcome in rheumatoid arthritis are only partly understood. Alterations in intestinal microflora are believed to be associated with disease activity in RA. Aim: To evaluate changes in short-chain fatty acid (SCFA) profiles and clinical outcome in RA during medical fasting or mediterranean diet. Methods: Fifty consecutive in-patients from an Integrative Medicine Department were included in a prospective observational, non-randomised, clinical trial. Patients underwent a 7-day fasting (MF) therapy or a Mediterranean diet (MD) as part of a multimodal therapeutic treatment approach. Results: The mean Disease Activity Score (DAS-28) significantly decreased in both groups (p < 0.001) from 5.7 ± 0.9 to 4.1 ± 1.3 in the MF and from 5.4 ± 1.4 to 4.5 ± 1.3 in the MG group, with no significant difference between the groups (p = 0.115). VAS showed a consecutive decrease of pain in both study groups which was significantly higher in the fasting group on day 7 (p = 0.049). No significant differences between the study groups were found in the profile of total-fatty acids (p = 0.069), butyrate (p = 0.611) and propionate (p = 0.419). Measurement of acetate, however, showed significant differences (p = 0.044) with an increase from 17,4 ± 9.8 µmol/g to 21,4 ± 16.4 µmol/g in MF compared to a decrease from 15,2 ± 10.4 µmol/g to 13,8 ± 9.3 µmol/g in MD. There was no significant correlation between dietary induced changes of SCFA and changes of disease activity. Conclusion: Alterations in SCFA were found in terms of significant changes to increased acetate levels in the fasting group. A correlation between changes of SCFA from intestinal microflora and disease activity in RA could not be revealed. Further studies are needed in the field of dietary inducible changes of the intestinal microflora in patients with RA.

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“…En el meta-análisis de la Cochrane, los efectos de la manipulación dietética, incluyendo dietas vegetarianas, mediterráneas, elemental y la eliminación de alimentación, en la artritis reumatoide son todavía inciertas debido a que se incluyeron estudios pequeños y ensayos individuales con moderado a alto riesgo de sesgo 41 . La dieta sin gluten vegana en la AR induce cambios que son potencialmente ateroprotectores y anti-inflamatorios, incluyendo la disminución de los niveles de LDL y oxLDL y los niveles de IgA 42 .…”

Section: Dieta Vegetariana Y Dieta Mediterráneaunclassified

Recomendaciones dietéticas en la artritis reumatoide

Alhambra-Expósito

Arjonilla-Sampedro

Molina-Puerta

et al. 2013

Rev Esp Nutr Hum Diet

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La artritis reumatoide es una enfermedad sistémica crónica, con gran impacto en la vida social, emocional y física de los pacientes. Desde hace décadas, se han utilizado distintas dietas para tratar de mejorar los síntomas de las personas que la padecen. En este artículo se revisan los posibles beneficios de la terapia dietética en la artritis reumatoide. Los objetivos nutricionales en esta patología son frenar la pérdida de masa ósea, favorecer la recuperación de fracturas óseas y mejorar los trastornos inflamatorios asociadas al hueso y a las articulaciones. En general, se recomiendan dietas bajas en grasas saturadas, ricas en grasas polinsaturadas: omega 3 y omega 6, en hidratos de carbono complejos y fibra. Recomendaciones dietéticas en la artritis reumatoide

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Dietary interventions for rheumatoid arthritis

Cited by 94 publications

References 39 publications

Chronic pain epidemiology – where do lifestyle factors fit in?

Chronic pain epidemiology – where do lifestyle factors fit in?

Changes of Intestinal Microflora in Patients with Rheumatoid Arthritis during Fasting or a Mediterranean Diet

Recomendaciones dietéticas en la artritis reumatoide

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