Dietary lipids and geriatric depression scale score among elders: The EPIC-Greece cohort

Kyrozis, Andreas; Ψαλτοπούλου, Θεοδώρα; Stathopoulos, Panos; Trichopoulos, D; Vassilopoulos, Dimitris; Trichopoulou, Antonia

doi:10.1016/j.jpsychires.2008.09.003

Cited by 53 publications

(41 citation statements)

References 49 publications

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“…Evidence also suggests that both ethanol (Imhof and Koenig, 2003) and nonalcoholic compounds (Sacanella et al 2007) (e.g., polyphenols of wine) appear to contribute to the potential anti-inflammatory effects of alcoholic beverages. Olive oil, a major component of Mediterranean diet, could partly explain Mediterranean diet beneficial effect in depression (Kyrozis et al 2009; Sanchez-Villegas et al 2011). However, very few studies suggest that oleic acid, a monounsaturated fatty acid, has anti-inflammatory effects (Basu et al 2006), but extra-virgin olive oil has phenolic compounds that has anti-inflammatory activities (Cicerale et al 2012).…”

Section: Discussionmentioning

confidence: 99%

Inflammatory dietary pattern and risk of depression among women

Lucas

Chocano-Bedoya

Shulze

et al. 2014

Brain, Behavior, and Immunity

167

114

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Backround Inflammation is considered as a mechanism leading to depression, but the association between inflammatory dietary pattern and depression risk is unknown. Methods Using reduced-rank regression, we identified a dietary pattern that was related to plasma levels of inflammatory markers (C-reactive protein, interleukin-6, tumor necrosis factor α receptor 2), and we conducted a prospective analysis of the relationship of this pattern and depression risk among participants in the Nurses’ Health Study. A total of 43,685 women (aged 50–77) without depression at baseline (1996) were included and followed up until 2008. Diet information was obtained from food frequency questionnaires completed between 1984 through 2002 and computed as cumulative average of dietary intakes with a 2-year latency applied. We used a strict definition of depression that required both self-reported physician-diagnosed depression and use of antidepressants, and a broader definition that included women who reported either clinical diagnosis or antidepressant use. Results During the 12-year follow-up, we documented 2,594 incident cases of depression using the stricter definition and 6,446 using the broader definition. After adjustment for body mass index and other potential confounders, relative risks comparing extreme quintiles of the inflammatory dietary pattern were 1.41 (95% confidence interval [CI], 1.22, 1.63; P-trend <.001) for the strict definition and 1.29 (95% CI, 1.18, 1.41; P-trend <.001) for the broader definition of depression. Conclusions The inflammatory dietary pattern is associated with a higher depression risk. This finding suggests that chronic inflammation may underlie the association between diet and depression.

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Section: Discussionmentioning

confidence: 99%

Inflammatory dietary pattern and risk of depression among women

Lucas

Chocano-Bedoya

Shulze

et al. 2014

Brain, Behavior, and Immunity

167

114

View full text Add to dashboard Cite

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“…Such an improved association was not found for mental status. Beyond the physical benefits reported for olive oil (Ló pezMiranda et al, 2010), recently, the protective role olive oil on mental disorders has been suggested by both cross-sectional (Kyrozis et al, 2009) as well as by prospective studies (Sánchez-Villegas et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Adherence to the Mediterranean diet and quality of life in the SUN Project

et al. 2011

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Background/Objectives: Mediterranean diet has been related with reduced morbidity and better well-being. The aim of this study was to assess whether the adherence to the Mediterranean diet were associated with mental and physical health related to quality of life. Subjects/Methods: This analysis included 11 015 participants with 4 years of follow-up in the SUN Project (a multipurpose cohort study based on university graduates from Spain). A validated 136-item food frequency questionnaire was used to assess the adherence to the Mediterranean diet at baseline, according to a nine-point score, presented in four categories (low, low-moderate, moderate-high and high). Health-related quality of life (HRQL) was measured after 4 years of follow-up with the Spanish version of the SF-36 Health Survey. Generalized Linear Models were fitted to assess adjusted mean scores, the regression coefficients (b) and their 95% confidence intervals (95% CIs) for the SF-36 domains according to categories of adherence to Mediterranean diet. Results: Multivariate-adjusted models revealed a significant direct association between adherence to Mediterranean diet and all the physical and most mental health domains (vitality, social functioning and role emotional). Vitality (b ¼ 0.50, 95% CI ¼ 0.32-0.68) and general health (b ¼ 0.45, 95% CI ¼ 0.26-0.62) showed the highest coefficients. Mean values for physical functioning, role physical, bodily pain, general health and vitality domains were significantly better with increasing adherence to the Mediterranean diet. Those having improved their initial high diet scores have better scores in physical functioning, general health and vitality. Conclusions: Adherence to the Mediterranean diet seems to be a factor importantly associated with a better HRQL.

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“…A population-based study conducted on 29,133 men of 50 to 69 years living in Finland reported no associations between the dietary intake of omega-3 fatty acids or fish consumption and depressed mood, major depressive episodes, or suicide [67]. Other inconclusive results regarding the association between omega-3 fatty acids and depression were reported in two minor population-based surveys (<1000 subjects) conducted in Australia [68] and Greece [69], although in the Greek one the 90th percentile of the GDS score (towards the high end) exhibited significant negative associations with monounsaturated fatty acids (MUFA) and olive oil [69]. Data from the nationwide Health 2000 Survey ( n = 5492) and the Fishermen Study on Finnish professional fishermen and their family members ( n = 1265) revealed a potential protective effect of general fish intake rather than intake or serum concentrations of omega-3 PUFA, although the associations were strongly influenced by lifestyle factors (i.e., high alcohol intake, occasional smoking, or having intermediate physical activity) [41].…”

Section: Evidence Of Efficacy Of Omega-3 Consumption Against Deprementioning

confidence: 99%

Omega-3 Fatty Acids and Depression: Scientific Evidence and Biological Mechanisms

Grosso

Galvano

Marventano

et al. 2014

Oxidative Medicine and Cellular Longevity

263

191

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The changing of omega-6/omega-3 polyunsaturated fatty acids (PUFA) in the food supply of Western societies occurred over the last 150 years is thought to promote the pathogenesis of many inflammatory-related diseases, including depressive disorders. Several epidemiological studies reported a significant inverse correlation between intake of oily fish and depression or bipolar disorders. Studies conducted specifically on the association between omega-3 intake and depression reported contrasting results, suggesting that the preventive role of omega-3 PUFA may depend also on other factors, such as overall diet quality and the social environment. Accordingly, tertiary prevention with omega-3 PUFA supplement in depressed patients has reached greater effectiveness during the last recent years, although definitive statements on their use in depression therapy cannot be yet freely asserted. Among the biological properties of omega-3 PUFA, their anti-inflammatory effects and their important role on the structural changing of the brain should be taken into account to better understand the possible pathway through which they can be effective both in preventing or treating depression. However, the problem of how to correct the inadequate supply of omega-3 PUFA in the Westernized countries' diet is a priority in order to set food and health policies and also dietary recommendations for individuals and population groups.

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Dietary lipids and geriatric depression scale score among elders: The EPIC-Greece cohort

Cited by 53 publications

References 49 publications

Inflammatory dietary pattern and risk of depression among women

Inflammatory dietary pattern and risk of depression among women

Adherence to the Mediterranean diet and quality of life in the SUN Project

Omega-3 Fatty Acids and Depression: Scientific Evidence and Biological Mechanisms

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