Dietary magnesium intake is protective in patients with periodontitis

Abstract

BackgroundPeriodontitis is a chronic inflammatory disease of the oral cavity characterized by inflammation of the periodontal tissue and resorption of the alveolar bone, which has a high incidence and is the main cause of tooth loss in adults. In addition to its role in promoting osteogenesis, magnesium also has a role in regulating the inflammatory response, both systemically and locally. There is growing evidence that magnesium is an important factor in maintaining the normal functioning of the body's immune system. Hypomagnesaemia can lead to a variety of chronic inflammatory diseases throughout the body, including periodontitis. Two-thirds of the US population suffers from magnesium deficiency. The connection between dietary magnesium and periodontitis is unknown. As a result, we set out to investigate the link between dietary magnesium intake and periodontitis.MethodsIn this study, we collected data from the National Health and Nutrition Examination Survey (NHANES) database from 2013 to 2014. Through 24-h dietary recalls, information about food consumption was collected. We examined the association between the dietary magnesium and periodontitis using multivariable logistic regression model. Based on odds ratios (OR) and 95% confidence intervals (CIs), a strong association was detected.ResultsMultivariable logistic regression analysis showed that the OR for periodontitis comparing the highest to the lowest quintile of dietary magnesium intake was 0.69 (95% CIs = 0.52~0.92). The restricted cubic spline (RCS) analysis showed that the non-linear association between dietary magnesium and periodontitis was statistically significant and that dietary magnesium supplementation reduced the prevalence of periodontitis.ConclusionDietary magnesium intake is associated with the prevalence of periodontitis. Dietary magnesium deficiency increases the prevalence of periodontitis.

Association between Dietary Habit and Clinical Parameters in Patients with Chronic Periodontitis Undergoing Supportive Periodontal Therapy

“…Deficiencies in vitamin C, vitamin E, and carotenoids, which have antioxidant properties, weaken the immune response [ 29 ]. Additionally, low consumption of dairy products, soy products, nuts, mackerel, and salmon induces deficiencies in calcium and magnesium, which are necessary minerals for strong teeth and bones and affect the pathophysiology of periodontal disease [ 30 ]. The purpose of this research was not only to conduct an epidemiological study of the association between nutritional factors and periodontal disease but also to identify the clinical parameters of periodontal disease that reflect nutritional factors through a detailed statistical analysis of inflammatory cytokine RNA levels in saliva from patients during SPT.…”

Sports nutrition supplements: Current dental perspective

“…Mg is a cofactor of SpxB catalytic activity and supplementation increases H2O2 production in vitro, the ability of H2O2 to antagonize susceptible oral bacterial species, including caries-associated Streptococcus mutans, as well as several periodontal pathobionts, has been confirmed [32] . That is why in the oral cavity, low dietary magnesium intake or deficiency is associated with the prevalence of periodontitis [33] . Recently, an association has been demonstrated between low serum Mg concentrations or Mg intake and increased atherosclerosis, coronary artery disease, arrhythmias and heart failure [34] .…”

Serum Vitamin D Affects the Association Between Cadmium and abdominal aorta calcification: A Cross- Sectional Study

“…Data on lifestyle factors, such as smoking and alcohol consumption, were also included. Smoking status, duration, and behavior were recorded using NHANES [21]. Alcohol consumption was determined based on at least 12 drinking criteria recorded in the NHANES 2013-2014 Alcohol Consumption Status [22].…”