Dietary mercury exposure in a population with a wide range of fish consumption — Self-capture of fish and regional differences are important determinants of mercury in blood

Jenssen, Marthe Torunn Solhaug; Brantsæter, Anne Lise; Haugen, Margaretha; Meltzer, Helle Margrete; Larssen, Thorjørn; Kvalem, Helen Engelstad; Birgisdóttir, Bryndís Eva; Thomassen, Yngvar; Ellingsen, Dag G.; Alexander, Jan; Knutsen, Helle Katrine

doi:10.1016/j.scitotenv.2012.09.024

Cited by 50 publications

(50 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mercury concentrations in hair have been associated with fish consumption as described previously in Mørck et al (10), which has also been confirmed in DEMO-COPHES (2,23) and in other studies (46)(47)(48)(49).…”

Section: All Biomarkers In the Studysupporting

confidence: 78%

Biomonitoring of Danish school children and mothers including biomarkers of PBDE and glyphosate

Knudsen

Hansen

Mizrak

et al. 2017

Reviews on Environmental Health

View full text Add to dashboard Cite

AbstractBackground:The Danish part of the large European Human biomonitoring pilot project Demonstration of a study to Coordinate and Perform Human biomonitoring on a European Scale (DEMOCOPHES) investigated the urine, hair and blood concentrations of 66 different environmental chemicals in a group of 145 Danish school children aged 6–11 years and their mothers from rural and urban areas in autumn 2011. Some – but not all – results were published; however, the concurrence of the chemicals has not been assessed.Methods:The measured concentrations of polybrominated diphenyl ethers (PBDEs) and glyphosate is assessed to complete the investigation of all 66 chemicals in DEMOCOPHES. The concentrations of PBDEs were measured in plasma samples of 143 mothers and 116 children. Glyphosate was measured in a subsample of 27 urine samples. Previously assessed chemicals were polychlorinated biphenyls (PCBs), and polyfluoroalkyl substances (PFASs) analyzed in blood samples, mercury analyzed in hair, and phthalate metabolites, parabens, phenols, cadmium, paracetamol and cotinine analyzed in urine samples. Differences in concentrations between mothers and children were assessed, and the associations between the concentrations of the different environmental chemicals. investigated by correlation analysis.Results:PBDE47 was found in relatively high levels compared with previous Danish results in both mothers and children, with a significantly higher level in the children compared to their mothers. Glyphosate in concentrations around 1 ng/mL was detected in all 27 samples. The analyzed environmental exposures seem to follow a pattern where chemicals within the same classes are strongly correlated and where children and mothers are exposed to the same chemicals.Conclusion:The correlations between the measured environmental chemicals indicate that a specific exposure pattern may exist, where people who are highly exposed to one class of environmental chemicals also may be highly exposed to certain other classes. As some of the compounds were measured in higher levels in children compared to mothers, increased focus also on the exposure in young children is recommended. For more detailed investigation of specific exposure sources more studies with increased power and detailed questionnaires should be developed.

show abstract

Section: All Biomarkers In the Studysupporting

confidence: 78%

Biomonitoring of Danish school children and mothers including biomarkers of PBDE and glyphosate

Knudsen

Hansen

Mizrak

et al. 2017

Reviews on Environmental Health

View full text Add to dashboard Cite

show abstract

“…Lee et al (2012) reported a value of 16 mg/L as total Hg levels in the blood of individuals living close to fishing areas in Taiwan. In a similar study, Jenssen et al (2012) evaluated Hg concentrations in total blood Norwegian subjects with high fish consumption and observed that the concentrations of Hg in blood ranged from 0.60 to 30 mg/L, with a mean of 5.3 mg/L and Engström et al (2008) reported a value of 5.5 mg/L as mean concentrations of blood Hg in Swedish subjects that were exposed to MeHg via fish intake, this value is about 10-fold lower than the levels observed in the present work.…”

Section: Discussionmentioning

confidence: 77%

Effects of genetic polymorphisms on antioxidant status and concentrations of the metals in the blood of riverside Amazonian communities co-exposed to Hg and Pb

Barcelos

Souza

Oliveira

et al. 2015

Environmental Research

View full text Add to dashboard Cite

“…(39) . Contribution of Hg from different types of food groups and subgroups of seafood is presented as micrograms per day (mg/d), and the estimated dietary intake of Hg is presented as micrograms per kilogram of body weight (BW) per week (mg/kg BW per week) ranked into quintiles.…”

Section: Calculation Of Total Hg Exposurementioning

confidence: 99%

Prenatal mercury exposure and infant birth weight in the Norwegian Mother and Child Cohort Study

Vejrup

Brantsæter

Knutsen

et al. 2013

Public Health Nutr.

View full text Add to dashboard Cite

Objective: To examine the association between calculated maternal dietary exposure to Hg in pregnancy and infant birth weight in the Norwegian Mother and Child Cohort Study (MoBa). Design: Exposure was calculated with use of a constructed database of Hg in food items and reported dietary intake during pregnancy. Multivariable regression models were used to explore the association between maternal Hg exposure and infant birth weight, and to model associations with small-for-gestational-age offspring. Setting: The study is based on data from MoBa. Subjects: The study sample consisted of 62 941 women who answered a validated FFQ which covered the habitual diet during the first five months of pregnancy. Results: Median exposure to Hg was 0?15 mg/kg body weight per week and the contribution from seafood intake was 88 % of total Hg exposure. Women in the highest quintile compared with the lowest quintile of Hg exposure delivered offspring with 34 g lower birth weight (95 % CI 246 g, 222 g) and had an increased risk of giving birth to small-for-gestational-age offspring, adjusted OR 5 1?19 (95 % CI 1?08, 1?30). Although seafood intake was positively associated with increased birth weight, stratified analyses showed negative associations between Hg exposure and birth weight within strata of seafood intake. Conclusions: Although seafood intake in pregnancy is positively associated with birth weight, Hg exposure is negatively associated with birth weight. Seafood consumption during pregnancy should not be avoided, but clarification is needed to identify at what level of Hg exposure this risk might exceed the benefits of seafood.

show abstract

Dietary mercury exposure in a population with a wide range of fish consumption — Self-capture of fish and regional differences are important determinants of mercury in blood

Cited by 50 publications

References 39 publications

Biomonitoring of Danish school children and mothers including biomarkers of PBDE and glyphosate

Biomonitoring of Danish school children and mothers including biomarkers of PBDE and glyphosate

Effects of genetic polymorphisms on antioxidant status and concentrations of the metals in the blood of riverside Amazonian communities co-exposed to Hg and Pb

Prenatal mercury exposure and infant birth weight in the Norwegian Mother and Child Cohort Study

Contact Info

Product

Resources

About