Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease

Abstract

The cardiovascular and metabolic disorders, collectively known as cardiometabolic disease (CMD), are high morbidity and mortality pathologies associated with lower quality of life and increasing health-care costs. The influence of the gut microbiota (GM) in dictating the interpersonal variability in CMD susceptibility, progression and treatment response is beginning to be deciphered, as is the mutualistic relation established between the GM and diet. In particular, dietary factors emerge as pivotal determinants shaping the architecture and function of resident microorganisms in the human gut. In turn, intestinal microbes influence the absorption, metabolism, and storage of ingested nutrients, with potentially profound effects on host physiology. Herein, we present an updated overview on major effects of dietary components on the GM, highlighting the beneficial and detrimental consequences of diet–microbiota crosstalk in the setting of CMD. We also discuss the promises and challenges of integrating microbiome data in dietary planning aimed at restraining CMD onset and progression with a more personalized nutritional approach.

Insights into Gut Microbiome Composition in Hidradenitis Suppurativa: A Comprehensive Examination of Dietary Habits and Environmental Influences

“…Synbiotics, which are combinations of probiotics and prebiotics, may also be beneficial for the gut microbiome and HS symptoms, as they may synergistically enhance the effects of probiotics and prebiotics in HS patients. Fecal microbiota transplantation (FMT), which is the transfer of fecal matter from a healthy donor to a recipient, may also be beneficial for the gut microbiome and HS symptoms, as it may restore gut microbiome diversity and function and improve clinical outcomes in HS patients [ 39 , 40 , 41 , 42 ].…”

Mindfulness, Gut‐Brain Axis and Health Related Quality of Life: The Paradigm of IBD Patients

“…The convergence of mindfulness with the GBA opens a fascinating avenue for understanding how the intentional cultivation of present-moment awareness may impact not only psychological states but also the intricate balance of the gut microbiome and gut function. Furthermore, the role of nutrition in this paradigm cannot be overstated, as the symbiotic relationship between the gut microbiota and dietary patterns influences both physical and mental health [8].…”

Mindfulness, Gut–Brain Axis, and Health-Related Quality of Life: The Paradigm of IBD Patients

“…Exploring the intersection between mindfulness and the GBA can provide insights into how present-moment awareness influences psychological states, gut microbiome balance, and gut function. Nutrition plays a significant role here, as dietary patterns affect both physical and mental health through their impact on the gut microbiota [ 8 ]. An example of a prudent dietary pattern that has been extensively researched and found to be beneficial for both gut microbiota as well as overall physical and mental health, is the Mediterranean diet.…”