Dietary Pomegranate By-Product Alleviated the Oxidative Stress Induced by Dexamethasone in Laying Hens in the Pre-Peak Period

Abstract

This experiment was conducted to assess the inclusion of the by-products of pomegranate peels to ameliorate the harmful impacts of oxidative stress in the pre-peak period of laying hens. For this, 120 local Egyptian strain hens (Inshas hens) aged 24 weeks old were used in four treatments. Pomegranate peel powder was included at 2% and 4% in the diets of laying hens subjected to oxidative injuries induced by dexamethasone compared with negative and positive control groups for 12 weeks. The addition of pomegranate peel powder (PPP) reduced the adverse effects of oxidative stress induced by dexamethasone on body weight (p = 0.006) and egg production (p = 0.010) comparing to the positive control. Additionally, pomegranate peel powder had a significant positive lowering effect on plasma cholesterol (p < 0.001) and triglyceride contents (p = 0.005) compared to control groups. The lipid peroxidation indicators (MDA) were reduced, but the antioxidative enzymes (SOD, CAT, and GPx) and total antioxidant blood capacity were improved with PPP. Based on the obtained data, the present research recommends using dietary PPP up to 4% to mitigate adverse oxidative stress effects in the pre-peak laying period and as a sustainable and economical approach for agricultural development.

Dietary phytogenic inclusion level affects production performance and expression of ovarian cytoprotective genes in laying hens

“…The animal capacity to mitigate oxidative stress is critical for the maintenance of egg production and hens’ health, especially in the prepeak period of laying, which can have long-lasting beneficial effects across the production period ( Finkel and Holbrook, 2000 ; Eid et al, 2021 ; Durand et al, 2022 ). Furthermore, it has been recently shown that the PP inclusion used in this work resulted in a consistent expression increase of cytoprotective genes and improved intestinal total antioxidant capacity ( TAC ), as well as an enhanced liver, breast meat and thigh meat TAC in broilers ( Mountzouris et al, 2019 , 2020 ).…”

Utilization of Agro-Industrial By-Products for Sustainable Poultry Production

“…In laying hen diets, supplementation with 2-4% pomegranate peel powder improved blood antioxidant activity and reduced plasma cholesterol and triglyceride content [169]. Pomegranate seed oil in hen diets enhanced laying rate, color, and concentrations of punicic acid and CLA in egg yolk [170].…”

Effects of dietary α-tocopherol acetate and pomegranate peel extract on growth performance and antioxidative potential and lipid oxidation of meat of broiler

“…Although the antioxidant activity of PP has been demonstrated by many scientific in vivo studies (Saleh et al, 2017;Al-Shammari et al, 2019;Kishawy et al, 2019;Sharifian et al, 2019;Akuru et al, 2020;Baset et al, 2020;Ahmadipour et al, 2021;Akuru et al, 2021;Eid et al, 2021)in broilers, there is currently no published in vivo research regarding the effects of the combined supplementation of α-tocopherol acetate (TA) and pomegranate peel extract (PPE) to the broiler diets enriched with omega-3 PUFAs.…”