Dietary Protein and Blood Pressure

Obarzanek, Eva; Velletri, Paul A.; Cutler, Jeffrey A.

doi:10.1001/jama.1996.03530440078040

Cited by 114 publications

(48 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Observational epidemiologic studies strongly support the hypothesis that raising protein intake lowers BP [31]. This inverse relationship has been documented in several populations, including Japanese rural farmers, Japanese-American men in Hawaii, American men in two cohort studies, British men and women, Chinese men and women, and American children.…”

Section: Increased Protein Intakementioning

confidence: 60%

The role of diet in the prevention and treatment of hypertension

Appel

2000

Curr Atheroscler Rep

View full text Add to dashboard Cite

An impressive body of evidence strongly supports the concept that multiple dietary factors influence blood pressure and that modification of diet can have powerful, beneficial effects on this highly prevalent, yet modifiable, cardiovascular risk factor. Dietary therapies with a proven ability to lower blood pressure include reduced sodium intake, weight loss, moderation of alcohol intake, increased potassium intake, and a diet that emphasizes fruits, vegetables, and low-fat dairy products that is low in fat and cholesterol. Several other dietary factors, such as an increased intake of protein or monounsaturated fatty acids, may also reduce blood pressure, but evidence to date is insufficient for policy recommendations. Still, widespread implementation of those therapies with a proven ability to lower blood pressure should have an enormous impact on the adverse patterns of blood pressure that remain highly prevalent in the United States and most other countries.

show abstract

Section: Increased Protein Intakementioning

confidence: 60%

The role of diet in the prevention and treatment of hypertension

Appel

2000

Curr Atheroscler Rep

View full text Add to dashboard Cite

show abstract

“…Although the success of variants of the DASH diet could have been due to a reduction in carbohydrate intake, several observational and clinical trials have left little doubt that high protein intake helps to lower blood pressure. [74][75][76] However, the source and type of the protein might be most important. 77 In a large, cross-sectional epidemiological study of 4,860 participants from four different countries, only protein from plant sources was associated with a reduction in blood pressure.…”

Section: Dash and Dash-like Dietsmentioning

confidence: 99%

“…78 Similar findings were noted in a systematic review of observational studies and clinical trials. 76,77 The relation ship between animal protein intake and blood pressure has been very inconsistent with some studies even suggesting an adverse effect on blood pressure. 79 The Protein and Blood Pressure (ProBP) study suggests that specific types of vegetable and animal protein might be bene ficial.…”

Section: Dash and Dash-like Dietsmentioning

confidence: 99%

Role of dietary therapies in the prevention and treatment of hypertension

2012

View full text Add to dashboard Cite

Blood pressure naturally rises with increasing age. The rate of change in blood pressure with age is regulated in part by genetic factors, but can also be altered through sustained dietary modification. Dietary approaches to modify blood pressure remain an important part of cardiovascular health promotion, which is especially important given the aging of the general population coupled with the increasing prevalence of obesity and metabolic disturbances. Specific modification of dietary components such as macronutrients and micronutrients could be helpful to lower blood pressure and alter the slope of blood pressure change whereas nutritional supplements are less likely to have a substantial beneficial effect. Population-wide generalizations regarding diet are impractical as individualized strategies are more likely to be successful in facilitating long-term benefits in improving blood-pressure control. Consequently, more effort needs to be focused on evaluating data from large-scale observational and interventional studies and interpreting their information in a clinically relevant manner, which is likely to be helpful for individual patients. Providing education on the relationship between diet and blood pressure from an early age is most likely to produce tangible benefits.

show abstract

“…Evidence regarding the influence of macronutrients on hypertension is limited. However, epidemiologic studies suggest that dietary protein may favorably affect blood pressure [46], though the role of animal versus plant protein remains debatable. Earlier epidemiologic data reported lower blood pressure levels in vegetarians compared with persons consuming animal products [47].…”

Section: Table 3 Putative Biologic Actions Of Soy Protein On Isoflavmentioning

confidence: 99%

“…It is hypothesized that specific amino acids found in both vegetable and animal proteins may mediate neurotransmitters in the brain and/or humoral substances that regulate vasodepressor responses. Tryptophan, tyrosine, taurine, and methionine are purported to possess hypotensive properties [46]. Arginine, commonly found in vegetable protein, specifically soy foods, is a precursor of nitric oxide (a potent vasodilator) and may facilitate blood pressure reduction as well [53].…”

Section: Table 3 Putative Biologic Actions Of Soy Protein On Isoflavmentioning

confidence: 99%

Effects of dietary animal and soy protein on cardiovascular disease risk factors

Hecker

2001

Curr Atheroscler Rep

View full text Add to dashboard Cite

A growing body of research offers insight into the influence of dietary protein on cardiovascular disease (CVD) risk. Early studies in rabbits indicated that animal protein was atherogenic; however, this has not been demonstrated in other animals species (pig, primate) or humans. More recent studies have found that low-fat animal protein can effectively improve some CVD risk factors. Soy protein has received much attention in recent years due to its seemingly marked effect on plasma cholesterol levels. However, further research has shown the hypocholesterolemic effect of soy protein to be most pronounced in cases of moderate to severe elevations in plasma lipids. Still, animal and soy protein sources contain a variety of bioactive components that may offer protection above and beyond cholesterol reduction. This review provides evidence that as part of a low-saturated fat diet, animal and/or soy protein intake at or above the recommended intake level of 15% of total calories lowers plasma cholesterol levels, reduces blood pressure, and potentially facilitates healthy weight management.

show abstract

Dietary Protein and Blood Pressure

Cited by 114 publications

References 34 publications

The role of diet in the prevention and treatment of hypertension

The role of diet in the prevention and treatment of hypertension

Role of dietary therapies in the prevention and treatment of hypertension

Effects of dietary animal and soy protein on cardiovascular disease risk factors

Contact Info

Product

Resources

About