Dietary protein and energy requirements in ESRD patients

Jd, Kopple

doi:10.1016/s0272-6386(98)70171-4

Cited by 35 publications

(8 citation statements)

References 19 publications

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“…This has also been observed by Slomowitz et al [19], who studied dietary energy requireabout 23-29 kcal/kg/day [12]. It has recently been reported that resting energy expenditure is higher in chronic ments in six stable MHD patients in a metabolic unit.…”

Section: Discussionsupporting

confidence: 66%

High Protein/Energy vs. Standard Protein/Energy Nutritional Regimen in the Treatment of Malnourished Hemodialysis Patients

Kuhlmann

Schmidt

Köhler

1999

Mineral Electrolyte Metab

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Although malnutrition is frequently encountered in maintenance hemodialysis (MHD) patients, a clear method of treating this complication is still lacking. Failure of nutritional support regimens may be due to inadequate support of dietary needs. Therefore, a high vs. standard or low protein/energy dietary regimen was studied in malnourished MHD patients. A total of 18 malnourished MHD patients selected according to subjective global assessment (SGA)-scores and biochemical indicators of malnutrition (serum albumin <40 g/l, cholesterol <200 mg/dl, prealbumin <30 mg/dl; two out of three) were assigned to three treatment groups: (A: 45 kcal/kg/d and 1.5 g protein/kg/d; B: 35 kcal/kg/d and 1.2 g protein/kg/d; C: spontaneous intake supplemented with 10% of mean protein and energy intake). A and B received food supplements at appropriate dosing to reach the targeted nutritional intake. During 3-month follow-up nutrient intake was assessed by repeated 4-day dietary diaries. Compliance and tolerance was good in each group. Weight gain (1.2±0.4 kg) was observed in group A, but not in B and C. Serum albumin levels increased by 1.0±0.5 g/l in group A, but not in B and C. Prealbumin and cholesterol levels were unaffected. Weight change correlated with mean dietary energy intake, but not with mean dietary protein intake. We conclude that prescription of 45 kcal/kg/d and 1.5 g protein/kg/d may be necessary to achieve weight gain and improvement of nutritional indices in malnourished MHD pts. Oral food supplements can be used safely and effectively to increase nutrient intake to high levels in these patients.

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Section: Discussionsupporting

confidence: 66%

High Protein/Energy vs. Standard Protein/Energy Nutritional Regimen in the Treatment of Malnourished Hemodialysis Patients

Kuhlmann

Schmidt

Köhler

1999

Mineral Electrolyte Metab

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“…In addition to the surveillance of patients for catabolic illness, one must ensure that adequate protein and caloric intake are provided. The currently recommended protein intake is 1.2–1.3 g/kg/day, while the recommended baseline caloric intake is 35–38 kcal/kg/day in PD patients (31).…”

Section: Malnutrition As a Cause Of Pd Mortalitymentioning

confidence: 99%

How Can Survival of the Well‐Dialyzed Patient Be Increased?

Tzamaloukas

Oreopoulos

2000

Seminars in Dialysis

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“…In addition, dietary patterns may have prognostic implications for patients through mechanisms independent of nutritional status. 22 23 However, data evaluating the association between diet and clinical outcomes in people treated with dialysis are limited and largely derive from small, single-centre, retrospective studies. 24–27…”

Section: Introductionmentioning

confidence: 99%

Nutrition and dietary intake and their association with mortality and hospitalisation in adults with chronic kidney disease treated with haemodialysis: protocol for DIET-HD, a prospective multinational cohort study

et al. 2015

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IntroductionAdults with end-stage kidney disease (ESKD) treated with haemodialysis experience mortality of between 15% and 20% each year. Effective interventions that improve health outcomes for long-term dialysis patients remain unproven. Novel and testable determinants of health in dialysis are needed. Nutrition and dietary patterns are potential factors influencing health in other health settings that warrant exploration in multinational studies in men and women treated with dialysis. We report the protocol of the “DIETary intake, death and hospitalisation in adults with end-stage kidney disease treated with HaemoDialysis (DIET-HD) study,” a multinational prospective cohort study. DIET-HD will describe associations of nutrition and dietary patterns with major health outcomes for adults treated with dialysis in several countries.Methods and analysisDIET-HD will recruit approximately 10 000 adults who have ESKD treated by clinics administered by a single dialysis provider in Argentina, France, Germany, Hungary, Italy, Poland, Portugal, Romania, Spain, Sweden and Turkey. Recruitment will take place between March 2014 and June 2015. The study has currently recruited 8000 participants who have completed baseline data. Nutritional intake and dietary patterns will be measured using the Global Allergy and Asthma European Network (GA2LEN) food frequency questionnaire. The primary dietary exposures will be n-3 and n-6 polyunsaturated fatty acid consumption. The primary outcome will be cardiovascular mortality and secondary outcomes will be all-cause mortality, infection-related mortality and hospitalisation.Ethics and disseminationThe study is approved by the relevant Ethics Committees in participating countries. All participants will provide written informed consent and be free to withdraw their data at any time. The findings of the study will be disseminated through peer-reviewed journals, conference presentations and to participants via regular newsletters. We expect that the DIET-HD study will inform large pragmatic trials of nutrition or dietary interventions in the setting of advanced kidney disease.

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Dietary protein and energy requirements in ESRD patients

Cited by 35 publications

References 19 publications

High Protein/Energy vs. Standard Protein/Energy Nutritional Regimen in the Treatment of Malnourished Hemodialysis Patients

High Protein/Energy vs. Standard Protein/Energy Nutritional Regimen in the Treatment of Malnourished Hemodialysis Patients

How Can Survival of the Well‐Dialyzed Patient Be Increased?

Nutrition and dietary intake and their association with mortality and hospitalisation in adults with chronic kidney disease treated with haemodialysis: protocol for DIET-HD, a prospective multinational cohort study

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