Dietary RNA is ripe for investigation

Witwer, Kenneth W.

doi:10.1038/d41586-020-01766-y

Cited by 3 publications

(2 citation statements)

References 6 publications

(5 reference statements)

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“…The main concern with oral sRNAs is how sRNAs travel across the mammalian gastrointestinal tract and transfer to a variety of tissues. Unravelling the mechanisms of delivery of sRNAs in mammalian cells would shed light on developing oral delivery‐based sRNA therapeutics (Chen et al, 2021; Witwer, 2020).…”

Section: Perspectivesmentioning

confidence: 99%

RNA silencing: From discovery and elucidation to application and perspectives

Zhao

Guo

2022

JIPB

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RNA silencing (or RNA interference, RNAi) is a conserved mechanism for regulating gene expression in eukaryotes. The discovery of natural trans-kingdom RNAi indicated that small RNAs act as signaling molecules and enable communication between organisms in different kingdoms. The phenomenon and potential mechanisms of trans-kingdom RNAi are among the most exciting research topics. To better understand trans-kingdom RNAi, we review the history of the discovery and elucidation of RNAi mechanisms. Based on canonical RNAi mechanisms, we summarize the major points of divergence around RNAi pathways in the main eukaryotes' kingdoms, including plants, animals, and fungi. We review the representative incidents associated with the mechanisms and applications of trans-kingdom RNAi in crop protection, and discuss the critical factors that should be considered to develop successful trans-kingdom RNAi-based crop protection strategies.

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Section: Perspectivesmentioning

confidence: 99%

RNA silencing: From discovery and elucidation to application and perspectives

Zhao

Guo

2022

JIPB

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“…A few weeks after its publication, Nature retracted Witwer's article, at his request. As is now indicated in the retraction notice available on Nature 's website: ‘The sponsorship and full scope of the supplement were not made clear to [the author] during the editing process’ (Witwer, 2020).…”

Section: A Difficult Equilibrium: Profit Seeking Versus Scientific In...mentioning

confidence: 99%

Expanding Nature: Product line and brand extensions of a scientific journal

Khelfaoui

Gingras

2021

Learned Publishing

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Academic publishers now market their most prestigious journals as commercial brands. This paper investigates this trend in the scholarly publishing market, by analyzing how the successive owners of the journal Nature have capitalized on its reputation to generate additional profits to those already accumulated through university library subscriptions. Two branding strategies of the journal Nature are analyzed: the first one, product line extension, consists in extending the Nature brand in the same product category, by creating an ever-increasing number of derived Nature journals; the second one, brand extension, consists in extending the Nature brand to other categories of products and services, such as academic rankings, sponsored supplements, feature advertisements, or webinars and trainings. The Nature brand leveraging strategy has been imitated by many other journal publishers. These branded products and services are well suited to the particular dynamics of the scientific field, which is based on the continuous quest for recognition. They are thus sold at all stages of the research cycle, from writing grants to popularizing research results, to scientists and academic institutions competing to accumulate symbolic capital. In this respect, academic publishers that engage in scholarly journal branding contribute to the transformation of the scientific 'community' into a scientific market.

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Author retracts article from Nature after raising concerns about sponsorship

Griffin¹

2020

BMJ

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Dietary RNA is ripe for investigation

Cited by 3 publications

References 6 publications

RNA silencing: From discovery and elucidation to application and perspectives

RNA silencing: From discovery and elucidation to application and perspectives

Expanding Nature: Product line and brand extensions of a scientific journal

Author retracts article from Nature after raising concerns about sponsorship

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