Dietary uptake in pike (Esox lucius) of some polychlorinated biphenyls, polychlorinated naphthalenes and polybrominated diphenyl ethers administered in natural diet

Abstract

The dietary uptake of 12 halogenated diaromatic compounds was studied using northern pike (Esox lucius L.) fed with rainbow trout (Oncorhynchus mykiss (Walbaum)). Before the trout were fed to the pike, they had been injected with a cocktail of five polychlorinated biphenyls, four polychlorinated naphthalenes, and three polybrominated diphenyl ethers, dissolved in rainbow trout lipid. The reported uptake efficiencies (E) were in the range 35 to 90% and differ in some respect from earlier studies. The E-values for those substances with effective cross sections (ECS) Ͼ9.5 Å were considerably higher than expected if the membrane permeation at dietary uptake was restricted as proposed previously in the literature. There was no hydrophobicity dependency of the total dietary uptake efficiency as suggested by an earlier proposed empirical model. The difference between the results presented here and earlier studies is likely to depend on cotransport with lipids and/or proteins through a mediated, possibly active uptake of hydrophobic organic compounds (HOC) in the gastrointestinal tract enabled by the actual exposure method. For the proposed mediated/active uptake of HOCs, the uptake efficiency varied with molecular weight and was greatest for a molecular weight of approximately 450.

Bioaccumulation and biotransformation of 61 polychlorinated biphenyl and four polybrominated diphenyl ether congeners in juvenile American kestrels (Falco sparverius)

“…The above trends in retention of PBDEs cannot be explained by differences in dietary assimilation efficiencies, because uptake efficiencies for BDE 47 were high (82% in rats [41] and Ͼ90% in fish [42]). Burreau et al [42] demonstrated that BDE dietary assimilation efficiencies decreased in fish with increasing degree of bromination, which is opposite to the trend observed for BDE dietary retention in American kestrels. Decreases in BDE dietary assimilation efficiencies with increasing degrees of bromination were not accounted for in modelestimated, congener-specific k b values; therefore, the data presented for half-lives may be somewhat underestimated, particularly for BDE 153.…”

Dietary absorption efficiencies and toxicokinetics of polychlorinated biphenyls in ring doves following exposure to aroclor® mixtures

“…Drouillard and R.J. Norstrom K ow Ͻ 5) chemicals. Other studies examining PCB AbEs in fish failed to show strong relationships between dietary AbEs and chemical K ow [32,33]. If solubility limitations in the aqueous phase of the UWL were indeed regulating chemical AbEs, one might predict that the rate of fecal egestion of chemicals would be inversely proportional to their aqueous solubilities.…”

Endocrine disruption in aquatic systems: up‐scaling research to address ecological consequences

“…Biotic and abiotic processes can influence the trophic transfer of EDCs within aquatic ecosystems. Alkylphenols, pyrethroids, polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) and diclofenac have been shown to partition, accumulate and magnify within components of aquatic food webs (see Table 1) and exhibit different entry and transfer pathways within the environment (Burreau et al, 1997(Burreau et al, , 2006Correa-Reyes et al, 2007;Corcellas, Eljarrat & Barcelo, 2015;Muggelberg et al, 2017). Many EDCs are hydrophobic in nature and readily partition out of the water column through adsorption to both suspended and benthic sediments (Petrović et al, 2001).…”