1985
DOI: 10.1016/s0140-6736(85)91694-0
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Dietary Vitamin D and Calcium and Risk of Colorectal Cancer

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Cited by 46 publications
(17 citation statements)
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“…Milk is also a major source of dietary calcium. Others have shown a protective effect of calcium on the development of colon cancer (Heilbrun et al, 1985;Garland et al, 1985); however, calcium has not been associated with bladder cancer risk and the mechanism by which calcium may alter bladder cancer risk is unknown.…”
Section: Discussionmentioning
confidence: 99%
“…Milk is also a major source of dietary calcium. Others have shown a protective effect of calcium on the development of colon cancer (Heilbrun et al, 1985;Garland et al, 1985); however, calcium has not been associated with bladder cancer risk and the mechanism by which calcium may alter bladder cancer risk is unknown.…”
Section: Discussionmentioning
confidence: 99%
“…When the relationships between colorectal cancer and dietary or supplementary vitamin D have been investigated in cohort studies of men [74,75] and women [76][77][78] or both sexes [79,80], and in case-control studies [81][82][83][84][85][86][87][88], the majority of studies suggested inverse associations for colon or rectal cancer, or both [74-77, 80, 82, 84, 86, 87]. Most importantly, all the studies of colorectal cancer that took into account supplementary vitamin D reported an inverse association.…”
Section: Colorectal Cancermentioning
confidence: 99%
“…Heilbrun et al (1985) used a case-control study nested within a prospective study of 8,006 Japanese men. The ageadjusted OR for colon cancer, when comparing the lowest quintile of calcium intake with the highest, was 1.3.…”
Section: Discussionmentioning
confidence: 99%
“…Several studies examined the role of calcium on different sites of the digestive tract, for instance pancreas and stomach (Guo et al, 1990;You et al, 1988), duodenum (Appleton et al, 1987) and colon and rectum. Some epidemiological studies report that ingestion of high levels of calcium has been associated with decreased risk of colon cancer (Garland et al, 1985; Slattcry et al., 1988;Newmark et al, 1984;Rozen et al, 1982;Heilbrun et al, 1985) while others indicate no association (Heilbrun et al, 1986; Stemmermann et al, 1990). In several experimental studies, ingestion or even infusion of high levels of calcium reduced colon tumorigenesis (Wargovich et al, 1983(Wargovich et al, , 1990Rafter et al, 1986;Bird, 1986;Newmark et al, 1985;Pence and Buddingh, 1988;Graham and Sackman, 1983;Reshef et al, 1990), but not all studies (GrCgoire et a/., 1989;Stern et a/., 1990).…”
mentioning
confidence: 99%