2011
DOI: 10.1088/0031-9155/56/18/013
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Difference-frequency generation in vibro-acoustography

Abstract: Vibro-acoustography (VA) is a medical imaging method based on the nonlinear interaction of two or more distinct ultrasound beams whose frequencies differ by several kHz. In turn, the interacting waves produce a difference-frequency signal which carries the information of the imaged tissue region. Two mechanisms are responsible for the difference-frequency generation (DFG) in VA, namely the dynamic (oscillatory) radiation force and the scattering of sound-by-sound. The role and importance of each phenomenon in … Show more

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Cited by 21 publications
(16 citation statements)
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“…For rigid movable objects, S2 is decomposed into D2 and R2. The D2 component p D2 is given by Equation (25) with boundary condition (36). The R2 component p R2 is given by Equation (25) with boundary condition (37), where the centroidal motion is determined from the wave-exciting force by Equation (39).…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…For rigid movable objects, S2 is decomposed into D2 and R2. The D2 component p D2 is given by Equation (25) with boundary condition (36). The R2 component p R2 is given by Equation (25) with boundary condition (37), where the centroidal motion is determined from the wave-exciting force by Equation (39).…”
Section: Discussionmentioning
confidence: 99%
“…Greenleaf et al, proposed measuring an object's difference frequency response from primary wave insonification for applications in medical ultrasound where significant interest in this exists [4,5]. Without a complete theoretical formulation for the second order field in the presence of a movable object, it was noted that the interaction of primary scattered waves may dominate the second order field [36,43,44] and mask information about the object's difference frequency response contained in weaker field components. Such a complete theory, as presented here, is necessary to investigate the conditions under which an object's difference frequency response may be detectable and when each of the various second order mechanisms may dominate.…”
Section: Discussionmentioning
confidence: 99%
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“…Greenleaf and colleagues developed this original idea (Fatemi and Greenleaf, 1999), generating interesting images of arterial plaque, defects in industrially derived materials and other relevant examples where variations in stiffness can be expected. One may fi nd a detailed study of the physics of vibroacoustography in Silva and Mitri (2011).…”
Section: Acoustic Radiation Pressurementioning
confidence: 99%
“…With the DF transmission, not only the second harmonic signal at 2f 0 band but also the inter-modulation harmonic signal at f 0 band will be generated within the pass band of the transducer during the nonlinear propagation of the acoustic waveform. Note that the intermodulation between DF acoustic beams is also utilized to monitor the tissue stiffness in the vibro-acoustography by vibration the tissue at the difference frequency [6,7]. By spectral compounding, the simultaneous DF harmonic imaging has the advantage of high contrast-to-noise ratio and high axial resolution [8].…”
Section: Introductionmentioning
confidence: 99%