Difference in end-tidal carbon dioxide between asphyxial cardiac arrest and ventricular fibrillation/pulseless ventricular tachycardia cardiac arrest in cardiopulmonary resuscitation—Comparison of 2000 and 2005 CPR guidelines

Vujanović, Vitka; Križmarić, Miljenko; Grmec, Štefek

doi:10.1016/j.resuscitation.2010.09.241

Cited by 2 publications

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“…Longer-lasting tissue hypoperfusion due to disease causes lactic acidosis [4,6] which leads to compensatory tachypnea and respiratory alkalosis [7][8][9]. If homeostasis is not achieved, the deepening of metabolic acidosis leads to respiratory failure, which results in secondary CA presented as an initial non-shockable rhythm, and higher levels of end-tidal carbon dioxide (EtCO 2 ) and lactate are expected [4,8,[10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Dynamics of Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest

Vujanović,

Borovnik Lesjak,

Mekiš

et al. 2023

Medicina

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Background and Objectives: An effective strategy for cardiopulmonary resuscitation should be based on tissue perfusion. Our primary aim was to determine the association between capillary lactate values and initial rhythm as well as the probability of the return of spontaneous circulation in out-of-hospital cardiac arrest patients. Materials and Methods: This prospective observational cohort study included all patients with non-traumatic out-of-hospital cardiac arrest, older than 18 years, resuscitated by a prehospital emergency medical team between April 2020 and June 2021. Capillary lactate samples were collected at the time of arrival and every 10 min after the first measurement until the time of the return of spontaneous circulation (ROSC) or, if ROSC was not achieved, at the time of declaring death on the scene. Results: In total, 83 patients were enrolled in the study. ROSC was achieved in 28 patients (33.7%), 21 were admitted to hospital (26.3%), and 6 (7.23%) of them were discharged from hospital. At discharge, all patients had Cerebral Performance Category Scale 1 or 2. Initial capillary lactate values were significantly higher in patients with a non-shockable rhythm compared to the group with a shockable rhythm (9.19 ± 4.6 versus 6.43 ± 3.81; p = 0.037). A significant difference also persisted in a second value taken 10 min after the initial value (10.03 ± 5,19 versus 5.18 ± 3.47; p = 0.019). Capillary lactate values were higher in the ROSC group and non-ROSC group at the time of restored circulation (11.10 ± 6.59 and 6.77 ± 4.23, respectively; p = 0.047). Conclusions: Capillary lactate values are significantly higher in patients with a non-shockable first rhythm in out-of-hospital cardiac arrest (OHCA). There is also a significantly different rise in capillary lactate levels in patients with ROSC.

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Section: Introductionmentioning

confidence: 99%

Dynamics of Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest

Vujanović,

Borovnik Lesjak,

Mekiš

et al. 2023

Medicina

View full text Add to dashboard Cite

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“…[7][8][9] If homeostasis is not achieved deepening of metabolic acidosis leads to respiratory failure which results in secondary CA presented initial non-shockable rhythm, higher levels of EtCO2 (end tidal carbon dioxide) and lactate are expected. [4,8,[10][11][12] Some studies showed poor neurological outcome of patients after return of spontaneous circulation (ROSC) with high levels of lactate at hospital admission. [13][14][15] A clear association between lactate levels and prognosis of OHCA still remains to be proven.…”

Section: Introductionmentioning

confidence: 99%

Dynamics of the Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest

Vujanović,

Borovnik Lesjak,

Mekiš

et al. 2023

Preprint

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Background and Objectives: Effective strategy to cardiopulmonary resuscitation should be based on tissue perfusion. Our primary aim was to determine the association between capillary lactate values and initial rhythm as well as probability of return of spontaneous circulation in out-of-hospital cardiac arrest patients. Materials and Methods: This prospective observational cohort study included all patients with non-traumatic out-of-hospital cardiac arrest, older than 18 years, resuscitated by a prehospital emergency medical team between April 2020 and June 2021. Capillary lactate samples were collected at the time of arrival and every 10 minutes after first measurement until the time of return of spontaneous circulation (ROSC) or if ROSC was not achieved at time of declaring death on scene. Results: 83 patients were enrolled in the study. ROSC was achieved in 28 patients (33,7%), 21 were admitted to the hospital (26,3%) and 6 (7,23%) of them were discharged from the hospital. At discharge all patients had Cerebral Performance Category Scale 1 or 2. Initial capillary lactate values were significantly higher in patients with non-shockable rhythm compared to the group with shockable rhythm (9,19 +/- 4,6 versus 6,43 +/- 3,81; p = 0.037). A significant difference persisted also in a second value taken 10 minutes after in-itial value (10,03 +/- 5,19 versus 5,18 +/- 3,47; p = 0.019). Capillary lactate values were higher in the ROSC group and non-ROSC group at the time of restored circulation (11,10 +/- 6,59 and 6,77 +/- 4,23, respectively; p = 0,047). Conclusions: Capillary lactate values are significantly lower in patients with a shockable first rhythm in OHCA. There is also a significant connection between a rise in capillary lactate level and ROSC.

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Difference in end-tidal carbon dioxide between asphyxial cardiac arrest and ventricular fibrillation/pulseless ventricular tachycardia cardiac arrest in cardiopulmonary resuscitation—Comparison of 2000 and 2005 CPR guidelines

Cited by 2 publications

References 0 publications

Dynamics of Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest

Dynamics of Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest

Dynamics of the Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest

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