Differences in Baseline Characteristics and Outcomes in Young Caucasians and African Americans with Acute Myocardial Infarction

Marroush, Tariq S.; Sharma, A.V.; Botros, Bassent; Szpunar, Susanna; Rosman, Howard; Mehta, Rajendra H.

doi:10.1016/j.amjms.2020.09.004

Cited by 3 publications

(4 citation statements)

References 19 publications

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“…This has resulted in an improved mortality from 17% in 1985–1990 to 6% in 2000–2008 1,2 . This change does not span equally among all races and sexes 3–7 . Prior data have demonstrated that women and minorities are less likely to receive revascularization with higher mortality and increased complications after STEMI 8,9 .…”

Section: Introductionmentioning

confidence: 99%

“… 1 , 2 This change does not span equally among all races and sexes. 3 , 4 , 5 , 6 , 7 Prior data have demonstrated that women and minorities are less likely to receive revascularization with higher mortality and increased complications after STEMI. 8 , 9 There is not much clarity regarding the factors responsible for reduced utilization of revascularization in female patients with STEMI.…”

Section: Introductionmentioning

confidence: 99%

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Racial disparities in women with ST elevation myocardial infarction: A National Inpatient Sample review of baseline characteristics, co‐morbidities, and outcomes in women with STEMI

Kumaran

Fratti

Desai

et al. 2023

Clinical Cardiology

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BackgroundA third of the patients admitted with Acute coronary syndrome (ACS) have ST‐elevation myocardial infarction (STEMI). Previous studies showed that females with STEMI have higher mortality than men.HypothesisThere exist significant disparities in outcomes among women of different races presenting with STEMI.MethodsNational inpatient sample (NIS) data was obtained from January 2016 to December 2018 for the hospitalization of female patients with STEMI. We compared outcomes, using an extensive multivariate regression analysis amongst women from different races. Our primary outcome was in‐hospital mortality. Secondary outcomes were revascularization use, procedure complications, and healthcare utilization.ResultsOf 202 223 female patients with STEMI; 11.3% were African American, 7.4% Hispanic, 2.4% Asian, and 4.3% another race. In‐hospital mortality was higher in non‐Caucasian groups. African American (adjusted odds ratio [aOR] 1.2; 95% confidence interval [CI]: 1.07–1.30; p < .01) and another race (aOR 1.37; 95% CI: 1.15–1.63; p < .01) had higher odds of mortality when compared with white women. African American (aOR 0.69; 95% CI: 0.62–0.72; p < .01), Hispanics (aOR 0.81; 95% CI: 0.74–0.88; p < .01), and Asian (aOR 0.79; 95% CI: 0.69–0.90; p < .01) had lower odds of percutaneous intervention (PCI) when compared with whites. African Americans had fewer odds of Coronary Artery Bypass Graft (CABG) and use of Mechanical Circulatory Support (MCS) during the index admission. Non‐Caucasians had more comorbidities, complications, and healthcare utilization costs.ConclusionThere are significant racial disparities in clinical outcomes and revascularization in female patients with STEMI. African American women have a higher likelihood of mortality among the different races. Females from minority groups are also less likely to undergo PCI.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Racial disparities in women with ST elevation myocardial infarction: A National Inpatient Sample review of baseline characteristics, co‐morbidities, and outcomes in women with STEMI

Kumaran

Fratti

Desai

et al. 2023

Clinical Cardiology

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“…AMI is extremely rare in young patients: in one study in Poland, individuals under age 40 represented only 1-6% of all AMI patients [2][3][4][5]. The rate of incidence has increased over years past in younger patients (< 35 years old) compared to older patients, and the age of onset is gradually falling, likely due to the following multiple risk factors such as smoking, obese, hypertension, diabetes, hyperlipidemia (higher level of low-density lipoprotein-cholesterol (LDL-C)), higher level of uric acid, history of coronary artery disease, family history of premature AMI, non-obstructive coronary artery disease (CAD), and genetic polymorphisms related to blood coagulation, fibrinogen, homocysteine, being present [3,[6][7][8][9]. Among previous reports, current age of onset was 19 years old [3,[6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

“…The rate of incidence has increased over years past in younger patients (< 35 years old) compared to older patients, and the age of onset is gradually falling, likely due to the following multiple risk factors such as smoking, obese, hypertension, diabetes, hyperlipidemia (higher level of low-density lipoprotein-cholesterol (LDL-C)), higher level of uric acid, history of coronary artery disease, family history of premature AMI, non-obstructive coronary artery disease (CAD), and genetic polymorphisms related to blood coagulation, fibrinogen, homocysteine, being present [3,[6][7][8][9]. Among previous reports, current age of onset was 19 years old [3,[6][7][8][9]. Age range between 19 and 29 years, and female sex were the only categories in which the number of patients with angiographically normal coronary arteries was higher than those with atherosclerotic CAD [3].…”

Section: Introductionmentioning

confidence: 99%

ST-Elevation Acute Myocardial Infarction in a Young Man

Usuda¹,

Tanaka²,

Suzuki³

et al. 2022

J Med Cases

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Acute myocardial infarction (AMI) in young patients is very rare, but the incidence has increased over years past at younger ages, likely due to the presence of multiple risk factors. We present the first known case of ST-elevation AMI (STEMI) in a young man. A 22-year-old Japanese man was transferred to our hospital due to suddenly occurred anterior chest pain. An electrocardiogram revealed ST elevation in anteroseptal leads together with reciprocal ST depression in inferior leads. An emergency coronary angiogram was performed, revealing a 100% occlusion at segment 6 of the coronary artery and we established a diagnosis of STEMI. The lesion was expanded to 0% stenosis through plain old balloon angioplasty, after which a third-generation drug-eluting stent was installed there. Afterwards, the patient was discharged on day 17. In this case, a combination of mild six risk factors plus family history of hypertension might lead to this atypical event.

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Disparities among Black and White patients in plaque burden and composition and long-term impact

Torguson

Mintz

Mario

et al. 2023

Cardiovascular Revascularization Medicine

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Differences in Baseline Characteristics and Outcomes in Young Caucasians and African Americans with Acute Myocardial Infarction

Cited by 3 publications

References 19 publications

Racial disparities in women with ST elevation myocardial infarction: A National Inpatient Sample review of baseline characteristics, co‐morbidities, and outcomes in women with STEMI

Racial disparities in women with ST elevation myocardial infarction: A National Inpatient Sample review of baseline characteristics, co‐morbidities, and outcomes in women with STEMI

ST-Elevation Acute Myocardial Infarction in a Young Man

Disparities among Black and White patients in plaque burden and composition and long-term impact

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