1986
DOI: 10.1159/000158652
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Differences in Function and Structure of the Capillary Endothelium in Gray Matter, White Matter and a Circumventricular Organ of Rat Brain

Abstract: Physiological and morphometric studies were conducted on the microvascular endothelium of four individual cerebral structures having different neural activities – the inferior colliculus, sensorimotor cortex (both gray matter regions), genu of the corpus callosum (white matter), and the subfornical organ (a circumventricular organ) of rats. The physiological data, obtained by quantitative autoradiography, produced new findings: (1) the rate of blood-to-tissue flux across capillary endothelial cells of a neutra… Show more

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Cited by 64 publications
(52 citation statements)
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“…Regional CBF has long been known to correlate with microvessel density (Gross et al, 1986), suggesting that increased thalamic blood flow is at least partly due to increased blood vessel density. This has been proposed for the cortex during 2 weeks after permanent ischemia in rats (Lin et al, 2002).…”
Section: Delayed Hyperperfusion Coincides With Angiogenesis In the Thmentioning
confidence: 99%
See 1 more Smart Citation
“…Regional CBF has long been known to correlate with microvessel density (Gross et al, 1986), suggesting that increased thalamic blood flow is at least partly due to increased blood vessel density. This has been proposed for the cortex during 2 weeks after permanent ischemia in rats (Lin et al, 2002).…”
Section: Delayed Hyperperfusion Coincides With Angiogenesis In the Thmentioning
confidence: 99%
“…Sensorimotor functions were examined and correlated with thalamic blood flow during the follow-up. Thalamic angiogenesis was studied by RECA-1 immunohistochemistry 3 months after cerebral ischemia, as regional CBF is known to correlate with microvessel density (Gross et al, 1986) and hemodynamic changes coincide with angiogenesis after ischemia in rats (Lin et al, 2002). In addition, we supposed that the expression of certain vascular growth factors and adhesion molecules is altered in the thalamus after cerebral ischemia, potentially contributing to angiogenesis.…”
Section: Introductionmentioning
confidence: 99%
“…In the present work, the blood vessels appeared dilated with distorted basement membrane. Since the inferior colliculus has one of the richest blood supply and greatest capillary densities in the nervous system (Gross et al, 1986). So, the observed severely degenerated nerve cells, fibers and disrupted blood vessels in the present study might be contributing factors in the hearing loss in elderly.…”
Section: Discussionmentioning
confidence: 50%
“…Differently again, hyperperfusion the ipsilateral thalamus was associated with a considerably increased vascular density. Although regional CBF has long been suggested to correlate positively with regional blood vessel density in healthy tissues (Gross et al, 1986), these results indicated very few links between CBF and chronic vascular reorganization after trauma. The fact that we found that the lower the CBF in the perilesional cortex, the higher the vascular density implies that cortical angiogenesis after TBI may not provide new vessels with sufficient vascular integrity to recover the chronic perfusion deficit.…”
Section: From Morphology To Function -Hemodynamic Alterations After Tbimentioning
confidence: 85%