Differences in Gut Microbiota Composition and Predicted Metabolic Functions: a Pilot Study of Adolescents with Normal Weight and Obesity

Klimenko, E. S.; Belkova, Natalia; Romanitsa, A. I.; Погодина, Анна; Rychkova, Lyubov; Darenskaya, M. A.

doi:10.1007/s10517-022-05601-4

Cited by 4 publications

(3 citation statements)

References 16 publications

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“…In addition, the microbiome and OS interaction in metabolic disorders [ 55 , 56 , 57 , 58 , 59 , 60 ], alcohol consumption [ 61 ], aging [ 62 ], and intestinal injury [ 63 ] have drawn attention. Although the number of studies in this field is rising every year, there are still many points to be clarified as well as unidentified molecules that might be relevant to this interaction.…”

Section: The Cooperation Of the Microbiome And Os In Disease Developm...mentioning

confidence: 99%

“…The other participants with active microflora were divided into three different groups and partly in the first one. In contrast, the β-diversity of all patients showed no differences in the main and control cohorts [ 57 ]. The parameters of OS in adolescents with obesity were also estimated in another study in a separate group.…”

Section: The Cooperation Of the Microbiome And Os In Disease Developm...mentioning

confidence: 99%

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Gut Microbiome Interactions with Oxidative Stress: Mechanisms and Consequences for Health

Semenova,

Garashchenko,

Kolesnikov

et al. 2024

Pathophysiology

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Understanding how gut flora interacts with oxidative stress has been the subject of significant research in recent years. There is much evidence demonstrating the existence of the microbiome–oxidative stress interaction. However, the biochemical basis of this interaction is still unclear. In this narrative review, possible pathways of the gut microbiota and oxidative stress interaction are presented, among which genetic underpinnings play an important role. Trimethylamine-N-oxide, mitochondria, short-chain fatty acids, and melatonin also appear to play roles. Moreover, the relationship between oxidative stress and the gut microbiome in obesity, metabolic syndrome, chronic ethanol consumption, dietary supplements, and medications is considered. An investigation of the correlation between bacterial community features and OS parameter changes under normal and pathological conditions might provide information for the determination of new research methods. Furthermore, such research could contribute to establishing a foundation for determining the linkers in the microbiome–OS association.

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Section: The Cooperation Of the Microbiome And Os In Disease Developm...mentioning

confidence: 99%

Section: The Cooperation Of the Microbiome And Os In Disease Developm...mentioning

confidence: 99%

Gut Microbiome Interactions with Oxidative Stress: Mechanisms and Consequences for Health

Semenova,

Garashchenko,

Kolesnikov

et al. 2024

Pathophysiology

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show abstract

“…За последние десятилетия были получены данные, свидетельствующие о существовании взаимосвязи между составом и функционированием бактериального сообщества кишечника человека и различными заболеваниями и состояниями организма. Благодаря более фундаментальному пониманию роли кишечного микробиома появились новые терапевтические стратегии и клинические подходы [1][2][3][4][5][6]. В последнее десятилетие широкое признание получила теория о том, что кишечник и мозг находятся в постоянной двунаправленной связи, основным компонентом которой является кишечная микробиота, и образуют так называемую ось «кишечник -мозг».…”

Section: Introductionunclassified

Melatonin and gut microbiome

Garashchenko,

Semenova,

Kolesnikova

2024

Acta biomedica scientifica

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In recent years, studies of the human microbiome have led to the development of the gut-brain axis theory, which proposes a relationship between the gut bacterial community and its metabolites and chemical compounds, as well as physiological and pathological processes in the brain. Melatonin is considered one of the potential links in this relationship.The review provides brief information about the synthesis, metabolism and effects of melatonin in the body. General patterns of the effect of melatonin on the intestinal microbiota under various conditions, such as oral and intraperitoneal melatonin administration, sleep deprivation, as well as the results of studying the microbial community with measurement of hormone levels are considered.Results are presented for families and individual genera of microorganisms and are obtained from studies in animal models or in the research of diseases. The article also notes some additional parameters which are supposed to be relevant to the interaction of melatonin with gut microbiome. Special attention is paid to butyrate as one of the most studied possible parts in this interaction. Studying the relationship between melatonin and microbiome is of interest for basic science and practical medicine.Literature search was carried out using electronic information resources PubMed and eLibrary.

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Alpha Diversity Indices as Indicators of the Variability of Gut Microbiota in Obese Adolescents of Different Ethnicities

Klimenko,

Belkova,

Rychkova

et al. 2024

Bull Exp Biol Med

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Differences in Gut Microbiota Composition and Predicted Metabolic Functions: a Pilot Study of Adolescents with Normal Weight and Obesity

Cited by 4 publications

References 16 publications

Gut Microbiome Interactions with Oxidative Stress: Mechanisms and Consequences for Health

Gut Microbiome Interactions with Oxidative Stress: Mechanisms and Consequences for Health

Melatonin and gut microbiome

Alpha Diversity Indices as Indicators of the Variability of Gut Microbiota in Obese Adolescents of Different Ethnicities

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