Differences in In Vitro Bacterial Adherence between Ti6Al4V and CoCrMo Alloys

Abstract

Prosthetic joint infection is an uncommon entity, but it supposes high costs, both from the economic side to the health systems and from the emotional side of the patient. The evaluation of the bacterial adherence to different materials frequently involved in joint prostheses allows us to better understand the mechanisms underlying this and provide information for the future development of prevention strategies. This study evaluated the bacterial adherence of four different species (Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa) on Ti6Al4V and CoCrMo. The topography, surface contact angles, and linear average roughness were measured in the samples from both alloys. The interaction with the surface of both alloys was significantly different, with the CoCrMo showing an aggregating effect on all the species, with additional anti-adherent activity in the case of Pseudomonas aeruginosa. The viability also changes, with a significant decrease (p < 0.05) in the CoCrMo alloy. In the case of S. epidermidis, the viability in the supernatant from the samples was different, too, with a decrease in the colony-forming units in the Ti6Al4V, which could be related to cation release from the surface. Beyond adhesion is a multifactorial and complex process, and considering that topography and wettability were similar, the chemical composition could play a main role in the different properties observed.

Fluoride anodic films on stainless-steel fomites to reduce transmission infections

“…There is no clear explanation for this difference. It could be due to the different susceptibility of the two species to the compounds in the anodic layer, the different adaptive responses to environmental changes, or even the fact that the different species may have different behavior when colonizing different materials, as has been the case with other organisms ( 46 ).…”

Prosthetic Joint Infections Caused by Mycobacterium tuberculosis Complex—An ESGIAI–ESGMYC Multicenter, Retrospective Study and Literature Review

“…Recent studies have demonstrated lesion heterogeneity, with host factors playing a crucial role in pathogenesis [20]. Furthermore, no studies on adherence or biofilm development onto the materials used in prostheses have been conducted; the potential for M. tuberculosis biofilm development on these surfaces may differ from what is described, as demonstrated in other microorganisms [21]. These factors could provide an explanation for the favorable outcomes observed in some cases, where surgery was not performed.…”