Differences in Lipid Profiles in Two Hispanic Ischemic Stroke Populations

Araúz, Antonio; Romano, José G.; Ruíz-Franco, Angélica; Shang, Ty; Dong, Chuanhui; Rundek, Tatjana; Koch, Sebastian; Hernández-Curiel, B.; Pacheco, Jennifer A.; Rojas, Pedro Navarro; Ruiz-Navarro, Francisco; Katsnelson, Michael; Sacco, Ralph L.

doi:10.1111/ijs.12239

Cited by 5 publications

(1 citation statement)

References 34 publications

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“…Some studies have attempted to disaggregate ethnic subgroups by ancestry and/or geographic region of origin to highlight differences in health characteristics due to heterogeneity. A stroke study by Arauz et al [ 13 ] explored the difference in lipid profiles between a predominantly Caribbean-Hispanic/Latino population in Miami, FL, U.S.A. and a predominantly Mestizo-Hispanic/Latino population in Mexico City, Mexico, ultimately finding significant differences in lipid profiles due to Hispanic/Latino racial or ethnic heterogeneity. Similarly, a nationwide population-based study by Chao et al [ 14 ] features higher PCa-specific mortality (PCSM) rates in Hawaiian and Pacific Islander men compared to NHW and other Asian American subgroups.…”

Section: Introductionmentioning

confidence: 99%

Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: a population-based study

et al. 2017

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BackgroundFew studies focus on prostate cancer (PCa) outcomes in Hispanic/Latino men. Our study explores whether Hispanic/Latino subgroups demonstrate significantly different prostate cancer-specific mortality (PCSM) relative to Non-Hispanic White (NHW) and Non-Hispanic Black (NHB) men.MethodsWe extracted a population-based cohort of men diagnosed with local-regional PCa from 2000-2013 (n= 486,865). PCSM was measured in racial/ethnic groups: NHW (n=352,886), NHB (n= 70,983), Hispanic/Latino (n= 40,462), and Asian American/Pacific Islander (n= 22,534). PCSM was also measured in Hispanic/Latino subgroups: Mexican (n= 8,077), Puerto Rican (n= 1,284), South or Central American (n= 3,021), Cuban (n= 788), and Dominican (n= 300). We conducted univariable and multivariable analyses (MVA) to compare risk for PCSM.ResultsCompared to NHW men, results showed worse outcomes for NHB men with similar outcomes for Hispanic/Latino men. In MVA with NHW men as a reference, NHB (HR= 1.15, p <0.001) men had significantly worse PCSM and Hispanic/Latino (HR= 1.02, p= 0.534) men did not show a significant difference. In a second MVA, Puerto Rican (HR= 1.71, p <0.001) and Mexican (HR= 1.21, p= 0.008) men had significantly higher PCSM. With NHB men as a reference, the MVA showed Puerto Rican (HR= 1.50, p= 0.006) men with higher PCSM and Mexican (HR= 1.08, p= 0.307) men with no significant difference.ConclusionsOur findings indicate previously unknown disparities in PCSM for Puerto Rican and Mexican American men.

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Section: Introductionmentioning

confidence: 99%

Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: a population-based study

et al. 2017

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Free fatty acid as an outcome predictor of atrial fibrillation–associated stroke

Choi

Jung

Kwon

et al. 2015

Annals of Neurology

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Metabolic Disturbances In The Patients With Acute Ischemic Stroke

Arabadzhieva

Kaprelyan

Georgieva

et al. 2014

Journal of Biomedical and Clinical Research

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Summary The purpose of this study was to analyze the disturbances of glucose, lipid and protein metabolism in acute ischemic stroke patients. A total of 258 patients (mean age 70.9±7.22 years, range 49-92 years) were studied. The following parameters were examined: blood glucose, triglycerides, total cholesterol, HDL-cholesterol, LDL-cholesterol, creatinine, and urea. Data were statistically processed by variation and correlation analysis. Our results demonstrated abnormal values of these laboratory parameters in most patients. The mean concentrations of triglycerides, total cholesterol and LDL-cholesterol were higher in females, while these of blood glucose were higher in males, especially in the age group between 76 and 80 years. Pearson’s correlation coefficient was highest between the variables ‘total cholesterol’ and ‘LDL-cholesterol’ (r=0.797) but moderate - between some of the rest variables such as ‘creatinine’ and ‘urea’ (r=0.575); ‘total cholesterol’ and ‘triglycerides’ (r=0.565); ‘total cholesterol’ and ‘urea’ (r=0.428); ‘triglycerides’ and ‘urea’ (r=0.370) and ‘LDL-cholesterol’ and ‘urea’ (r=0.301). In conclusion, the metabolic disorders are relatively common among acute ischemic stroke patients and play a specific role as risk factors for this disease. These parameters should regularly be controlled within the outpatient practice in order to warrant an effective prevention of acute ischemic stroke.

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Differences in Lipid Profiles in Two Hispanic Ischemic Stroke Populations

Cited by 5 publications

References 34 publications

Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: a population-based study

Ethnic heterogeneity and prostate cancer mortality in Hispanic/Latino men: a population-based study

Free fatty acid as an outcome predictor of atrial fibrillation–associated stroke

Metabolic Disturbances In The Patients With Acute Ischemic Stroke

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