Differences in management and outcome of ischemic and non-ischemic cardiomyopathy

Ng, A.; Sindone, Andrew; Wong, Helen; Freedman, Ben

doi:10.1016/j.ijcard.2007.07.014

Cited by 36 publications

(17 citation statements)

References 25 publications

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“…Therefore, a higher prevalence of comorbidities could increase the risk of non-cardiac death, which could be an important reason for the increased all-cause mortality in the ICMP group. Previous studies reported a difference in survival between NICMP and ICMP patients 11). Although NICMP patients were younger, patients with ICMP had poorer clinical outcomes than the NICMP patients 11)13).…”

Section: Discussionmentioning

confidence: 82%

“…Previous studies reported a difference in survival between NICMP and ICMP patients 11). Although NICMP patients were younger, patients with ICMP had poorer clinical outcomes than the NICMP patients 11)13). NICMP patients showed a greater improvement in symptoms and left ventricular function during follow-up 11).…”

Section: Discussionmentioning

confidence: 83%

“…The cause of cardiomyopathy was evaluated and classified as follows: ischemic cardiomyopathy (ICMP) was defined as left ventricular dysfunction associated with coronary artery disease (>50% narrowing of the diameter of at least one of the 3 major coronary arteries on coronary angiography), a history of a MI, a regional wall motion abnormality in the echocardiography, abnormal perfusion in single photon emission computerized tomography, or a Q wave in the electrocardiogram 11). NICMP was defined as left ventricular dysfunction without a definite cause by coronary lesion 11). In patients with acute MI, echocardiography data were used, which was measured at least 40 days after MI.…”

Section: Methodsmentioning

confidence: 99%

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The Relevance of the Primary Prevention Criteria for Implantable Cardioverter Defibrillator Implantation in Korean Symptomatic Severe Heart Failure Patients

et al. 2012

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Background and ObjectivesImplantable cardioverter defibrillator (ICD) therapy is recommended as the primary tool for prevention of sudden cardiac death (SCD) in symptomatic patients with severe left ventricular dysfunction. There is a paucity of information on whether this recommendation is appropriate for the Korean population with severe heart failure.Subjects and MethodsThe study group consisted of 275 consecutive patients (mean age 65 years, 71% male) who met the ICD implantation criteria for primary prevention (left ventricular ejection fraction ≤30% and New York Heart Association functional class II or III). We analyzed the clinical characteristics and outcomes of an ischemic cardiomyopathy (ICMP) group (n=131) and a non-ischemic cardiomyopathy (NICMP) group (n=144). The outcomes of these 2 groups were compared with the Multicenter Automatic Defibrillator Implantation Trial II (MADIT-II) conventional and Defibrillators in the Non-ischemic Cardiomyopathy Treatment Evaluation (DEFINITE) standard therapy groups, respectively.ResultsEighty patients (29%) died during a follow-up period of 40±17 months. The NICMP group had better all-cause mortality rates than the ICMP group (19% vs. 40%, p<0.001), however both groups had a similar incidence of SCD (7% vs. 10%, p=0.272). The 2-year all-cause mortality and SCD for the ICMP group were similar to those of the MADIT-II conventional therapy group (20% vs. 20%, 7% vs. 10%, respectively, all p>0.05). All-cause mortality and the incidence of SCD in the NICMP group were comparable to those of the DEFINITE standard therapy group (13% vs. 17%, 6% vs. 6%, respectively, all p>0.05).ConclusionKorean patients with severe heart failure in both the ICMP and NICMP groups had all-caused mortality and risk of SCD comparable to patients in the MADIT-II and DEFINITE standard therapy groups. Therefore, the primary prevention criteria for ICD implantation would be appropriate in both Korean ICMP and NICMP patients.

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Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 83%

Section: Methodsmentioning

confidence: 99%

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The Relevance of the Primary Prevention Criteria for Implantable Cardioverter Defibrillator Implantation in Korean Symptomatic Severe Heart Failure Patients

et al. 2012

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“…The prognosis is even worse for patients with ischemic rather than nonischemic cardiomyopathy [2] . Treatment options in ischemic cardiomyopathy include medical management with or without revascularization.…”

Section: Introductionmentioning

confidence: 99%

Medical management to full recovery in patients with severe ischemic cardiomyopathy

Fesel

Narveson

Marconi

et al. 2014

CRIM

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The role of coronary artery bypass grafting in the treatment of patients with ischemic cardiomyopathy and heart failure has not been clearly established. A few studies have suggested that patients with multivessel coronary artery disease and severe left ventricular dysfunction may have superior outcomes with surgery than with medical management. In this report we describe three patients with multivessel coronary artery disease, severe ischemic cardiomyopathy and advanced heart failure who experienced full and sustained clinical and echocardiographic recovery with medical management alone, without revascularization. These cases constitute "proof of concept" indicating that aggressive medical management may be an appropriate first-line therapy for such patients.

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“…Characteristics, treatment and outcomes of patients hospitalized with HF differ between patients with different etiology of heart failure such as ischemic or non-ischemic cardiomyopathy [4].…”

Section: Introductionmentioning

confidence: 99%

Temporal trends in the hospitalization and outcomes of patients with decompensated heart failure

Novack¹,

Jotkowitz²,

Porath³

2011

International Journal of Cardiology

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Differences in management and outcome of ischemic and non-ischemic cardiomyopathy

Cited by 36 publications

References 25 publications

The Relevance of the Primary Prevention Criteria for Implantable Cardioverter Defibrillator Implantation in Korean Symptomatic Severe Heart Failure Patients

The Relevance of the Primary Prevention Criteria for Implantable Cardioverter Defibrillator Implantation in Korean Symptomatic Severe Heart Failure Patients

Medical management to full recovery in patients with severe ischemic cardiomyopathy

Temporal trends in the hospitalization and outcomes of patients with decompensated heart failure

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