Differences of Heart Rate Variability during Sevoflurane Anesthesia in Children by Age

Abstract

Background: The child's central nervous system develops with aging, and heart rate variability (HRV), which is controlled by the brain, differs from that of adults. We investigated changes in HRV during sevoflurane anesthesia in children. Methods: One 138 children aged from 2 -12 years without major underlying problems were enrolled. During maintenance with 2 -2.5 vol% sevoflurane anesthesia, electrocardiographic data were obtained and power spectral analysis, approximate entropy (ApEn) or Hurst exponent were analyzed and compared in three groups (age 2 -5 years, 6 -9 and 10 -12 years of age). Results: The RR interval increased with aging, but low-frequency powers did not. Highfrequency power was greater in the oldest children (P < 0.05), while ApEn and Hurst exponents were lower (P < 0.05). Conclusion: Change in HRV is one of the characteristics of development in children.

Interactive Cardio System for Healthcare Improvement

“…For this purpose, HRV was studied using statistical methods and the obtained results indicated low values of HRV during strong negative emotions. Park, in [ 18 ], while applying a spectral analysis of HRV on the ECG of children, found a change in HRV during the growth of children.…”