Differences on the prevalence of cervical HPV between Lithuania and Belarus

Abstract

<jats:title>Abstract</jats:title><jats:p>In some countries the cervical cancer incidence and mortality rates are much higher compared to the European average. The differences of HPV and its type prevalence between countries and regions influence cervical cancer incidence and mortality. Regarding the differences in cervical cancer incidence and mortality in Lithuania and Belarus, the aim of this study was to describe HPV infection level and HPVs type distribution among two study groups of patients with moderate or severe cervical intraepithelial neoplasia (CIN2-3) and cervical cancer. Our data shows that 74.2% [95% CI: 63.64÷84.76] of Lithuanian patients with cervical cancer and 85.6% [95% CI: 85.53÷92.85] of the study group with CIN2-3 were HPV positive, while in the study groups of Belarusian patients HPV infection was detected in 92.6% [95% CI, 74.25÷98.71] and 65.4% [95% CI, 44.36÷82.06] cases respectively. HPV 16 was the most prevalent type in Lithuanian as well as in Belarusian patients of the study groups. HPV 18 in Lithuanian patients of the study group with cervical cancer was identified in 10.2% [95% CI: 1.73÷18.67] and in the study group with CIN2-3 — in 2.6% [95% CI: 0.95÷6.15] of cases. HPV 18 was not detected in Belarusian patients of both groups.</jats:p>

An Overview of Cervical Cancer Epidemiology and Prevention in the Baltic States

“…HPV 16 was the most prevalent subtype, detected in 50% of cervical cancers and CIN 2/3 cases, followed by ~ 10% prevalence of HPV 18 and HPV 33 in both disease groups. [22] Estonian data is closely mirroring these results -with prevalence of 55%, 12% and 8% for HPV 16, 33 and 31 respectively among women with high grade cervical lesions. [23] According to the study from Latvia by Silins et al (2004), the most common HPV DNA type found in cervical samples of the cervical cancer patients was HPV 16 (60.6%), followed by HPV 18 (9.0%), HPV 31 (5.4%), HPV 45 (3.2%), and HPV33 (2.7%).…”

An overview of cervical cancer epidemiology and prevention in the Baltic States

“…In Lithuania, 74.2% women with CIN2/3 and 85.6% of women with cervical cancer, were hrHPV positive. HPV 16 was the most prevalent subtype, detected in 50% of cervical cancers and CIN 2/3 cases, followed by ~ 10% prevalence of HPV 18 and HPV 33 in both disease groups [22]. Estonian data is closely mirroring these resultswith prevalence of 55%, 12% and 8% for HPV 16, 33 and 31 respectively among women with high grade cervical lesions [23].…”