Simple SummaryThe Five Freedoms were formulated in the early 1990s and are now well recognised as highly influential in the animal welfare arena. However, a marked increase in scientific understanding over the last two decades now shows that the Five Freedoms do not capture, either in the specifics or the generality of their expression, the breadth and depth of current knowledge of the biological processes that are germane to understanding animal welfare and to guiding its management. For example, this paper refers to some negative experiences that can never be eliminated, merely temporarily neutralised, because they are essential for eliciting behaviours upon which the survival of the animal depends. In addition, it refers to other negative experiences that relate to an animal’s responses to living in poor environments which require improvement, and also to how such experiences may be replaced by positive ones when particular improvements are introduced. For animals to have “lives worth living” it is necessary, overall, to minimise their negative experiences and at the same time to provide the animals with opportunities to have positive experiences. These observations have implications for reviewing and potentially updating minimum standards in codes of welfare. The paper ends with an up-to-date characterisation of the principal features of animal welfare, expressed largely in non-technical terms.AbstractThe Five Freedoms have had major impact on animal welfare thinking internationally. However, despite clear initial statements that the words ‘freedom from’ should indicate ‘as free as possible from’, the Freedoms have come to be represented as absolute or fundamental freedoms, even rights, by some animal advocate and other groups. Moreover, a marked increase in scientific understanding over the last two decades shows that the Freedoms do not capture the more nuanced knowledge of the biological processes that is germane to understanding animal welfare and which is now available to guide its management. For example, the named negative experiences of thirst, hunger, discomfort and pain, and others identified subsequently, including breathlessness, nausea, dizziness, debility, weakness and sickness, can never be eliminated, merely temporarily neutralised. Each one is a genetically embedded element that motivates animals to behave in particular ways to obtain specific life-sustaining resources, avoid or reduce physical harm or facilitate recovery from infection or injury. Their undoubted negativity creates a necessary sense of urgency to respond, without which animals would not survive. Also, the temporary neutralisation of these survival-critical affects does not in and of itself generate positive experience. This questions the commonly held assumption that good animal welfare will result when these internally generated negative affects are minimised. Animals may also experience other negative affects that include anxiety, fear, panic, frustration, anger, helplessness, loneliness, boredom and depression. These situa...