Different Approaches to Therapy of Depressive Disorders in Clinical Practice

Volel, Beatrisa A.; Сорокина, О. Ю.

doi:10.21518/2079-701x-2018-1-118-122

Med. sov.

2018

DOI: 10.21518/2079-701x-2018-1-118-122

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Different Approaches to Therapy of Depressive Disorders in Clinical Practice

Beatrisa A. Volel¹,

О. Ю. Сорокина²

Abstract: Депрессивные расстройства, являясь самой распространенной психической патологией в общесоматической практике, часто выступают в качестве причины утяжеления течения соматической/неврологической патологии, увеличения риска инвалидизации и смертности пациентов. Депрессии по своей клинической структуре неоднородны: наиболее часто встре-чаются в общей медицине невротические депрессии, нозогении/соматогении, а также соматореактивная циклотимия. В связи с разнообразием встречающихся клинических форм аффективных забол… Show more

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Cited by 2 publications

References 25 publications

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Chest pain as an interdisciplinary problem – emphasis on somatoform disorders

Petelin,

Isaeva,

Tolokonin

et al. 2024

Medicinskij sovet

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Chest pain of a non-cardiac nature is one of the extremely significant problems of clinical medicine, which is associated with the widespread prevalence of this condition and the high healthcare costs for diagnosing and treating such patients. Along with neurological, gastroenterological and pulmonological diseases, mental disorders make a major contribution to the formation of chest pain. Moreover, the formation of pain in the chest area can be associated not only with such well-known psychopathological conditions as depression and anxiety disorders, but also with the pathology of the somatoform circle. This review presents data on the frequency of chest pain associated with mental disorders (pain as a symptom of a mental disorder, mental disorders as a consequence of a previous episode of chest pain, etc.), the nature of the relationship between pain symptoms and mental disorders, as well as the clinical picture somatoform disorders manifesting in the form of thoracalgia. Information is summarized on approaches to diagnosing mental disorders in patients with chest pain and the possibilities for their psychopharmacotherapy and psychotherapy. When discussing psychopharmacotherapy, emphasis is placed on the possibilities of using the atypical tranquilizer tofisopam in this category of patients, and a brief description of its effectiveness and safety is given. To illustrate the main points of the review, a clinical case of a patient with chest pain of non-cardiac origin, which manifested itself after a traumatic event, which in turn provoked a myocardial infarction, is also presented. Positive dynamics with subsequent recovery during therapy with tofisopam are described.

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Chest pain as an interdisciplinary problem – emphasis on somatoform disorders

Petelin,

Isaeva,

Tolokonin

et al. 2024

Medicinskij sovet

Self Cite

View full text Add to dashboard Cite

show abstract

Depressive Disorders: In Population, in Gastroenterological Patients and in Covid-19 Period

Stepanov¹,

Demeshkіna²,

Mosiychuk³

et al. 2021

Journal NAMSU

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Introduction. There are some data that suggest that emotional stress and depression may affect the development of functional organic disorders of the gastrointestinal tract. However, the relationship between them is not fully understood. It is not unknown the relationship between stress / depression and chronic gastritis. Aim: to analyze the published articles and online sources on depressive disorders with an emphasis on the impact of the COVID-19 pandemic, and investigate the depression level in patients with chronic atrophic gastritis with intestinal metaplasia, with or without gastric dysplasia. Materials and methods. Literature data were studied for 2004-2021 using Internet resources in English, Ukrainian, and Russian language. Using the HADS scale («The hospital Anxiety and Depression Scale»), the level of depression was studied in 76 patients with chronic atrophic gastritis (with intestinal metaplasia, with or without gastric dysplasia). Statistical data analysis was performed with SPSS Version 13.0. Results. Having used Internet resources and scientific publications, depressive manifestations, according to the International Classification of Diseases (ICD-10), diagnostic methods, the prevalence of depressive disorders before and during the pandemic COVID-19, as well as the impact of COVID-19 on the severity of depressive manifestations were studied. Additionally, it was found in this study that 23.7 % of patients with chronic atrophic gastritis had depressive changes. 13.2 % of these changes were subclinically expressed, and 10.5 % of ones were clinically expressed and required psychocorrective therapy. Conclusions. The COVID-19 pandemic is a trigger in society that may exacerbate depression in patients with other comorbid diseases and in the general population. Depressive changes requiring psychocorrective therapy were revealed in 23.7 % of patients with chronic atrophic gastritis with intestinal metaplasia. Keywords: Depression, general population, COVID-19, chronic atrophic gastritis, intestine metaplasia, dysplasia.

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Different Approaches to Therapy of Depressive Disorders in Clinical Practice

Cited by 2 publications

References 25 publications

Chest pain as an interdisciplinary problem – emphasis on somatoform disorders

Chest pain as an interdisciplinary problem – emphasis on somatoform disorders

Depressive Disorders: In Population, in Gastroenterological Patients and in Covid-19 Period

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