Different drug loading methods and antibiotic structure modulate the efficacy of polydopamine nanoparticles as drug nanocarriers

Abstract

The inefficient delivery of antimicrobials to their target is a significant factor contributing to antibiotic resistance. As such, smart nanomaterials that respond to external stimuli is extensively explored for precise...

The Use of Photoactive Polymeric Nanoparticles and Nanofibers to Generate a Photodynamic-Mediated Antimicrobial Effect, with a Special Emphasis on Chronic Wounds

“…Loading drugs can occur either during the synthesis process of PDA or as a separate post-synthetic step, and the drug release can be stimulated by laser irradiation, or it may follow a passive route. In this way, PDA can be tailored, in its synthesis and properties, to be a drug delivery system [ 76 ]. It was shown that the encapsulation efficacy of Ce6 in mesoporous PDA nanoparticles reached around 69.64% [ 77 ].…”