Different exercises for pregnant women with gestational diabetes: a meta-analysis of randomized controlled trials

Huang, Xuena; Huang, Jingxing; Wu, Jiezhu; Li, Min; Yang, Ziqing; Liu, Liuhong; Lin, Tian; Lan, Yutao; Chen, Ken

doi:10.23736/s0022-4707.19.10131-4

Cited by 14 publications

(8 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because only one person in each group took insulin, more samples are needed to verify the results in the future. Thus far, studies have reported relatively consistent findings on the positive effects of resistance exercise and aerobic exercise on blood glucose level and insulin use, respectively,27 30 and the findings of the present study agreed with those of previous studies. Resistance exercise can promote skeletal muscle cells to increase the utilization and uptake of glucose, enhance glucose phosphorylation in muscle cells, promote the conversion of blood glucose to monosaccharide, maintain the insulin secretion and balance of glucose, and ultimately reduce blood glucose level 31 32.…”

Section: Discussionsupporting

confidence: 93%

“…Presently, there is no evidence that resistance exercise or aerobic exercise causes adverse effects on women with GDM and their infants, and it does not increase the incidence of adverse pregnancy outcomes such as neonatal hyperbilirubinemia, macrosomia, and cesarean section 14 15 24–26. Previous studies have also shown that a lack of exercise during pregnancy can increase the incidence of depression, anxiety, etc,27–29 indicating that exercise for women with GDM is safe to a certain extent and conducive to their happiness.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of resistance exercise on blood glucose level and pregnancy outcome in patients with gestational diabetes mellitus: a randomized controlled trial

Xie

Zhao

Meijing

et al. 2022

BMJ Open Diab Res Care

View full text Add to dashboard Cite

IntroductionTo date, the effects of resistance exercise on diabetes-related parameters (blood glucose level and insulin use) and pregnancy outcome in participants with gestational diabetes mellitus (GDM) have not been compared with those of aerobic exercise. To investigate the effect of resistance exercise versus aerobic exercise on blood glucose level, insulin utilization rate, and pregnancy outcome in patients with GDM.Research design and methodsFrom December 2019 to December 2020, 100 pregnant women with GDM were selected and divided into a resistance exercise group (49 patients) and an aerobic exercise group (51 patients) randomly. The aerobic exercise group received an aerobic exercise intervention, while the resistance exercise group received a resistance exercise intervention. Both groups received exercise intervention for 50–60 min, 3 times per week, lasting for 6 weeks. In addition, patients in both groups received the same routine care, including personalized dietary intervention, online education, and school courses for pregnant women.ResultsThe blood glucose level in the resistance exercise group and the aerobic exercise group was lower after the intervention than before the intervention (p<0.05). After the intervention, no significant differences were observed in the fasting blood glucose level, insulin utilization rate, and incidence of adverse pregnancy outcomes between the two groups (p>0.05); however, significant differences were noted in 2-hour postprandial blood glucose level and exercise compliance between the two groups (p<0.05), with the resistance exercise group showing better outcomes than the aerobic exercise group.ConclusionsResistance exercise is more compliant for pregnant women with GDM than aerobic exercise; hence, it is necessary to popularize resistance exercise in this specific population group. Long-term effects of resistance exercise should be evaluated in future studies.Trial registration numberChiCTR 1900027929.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Effects of resistance exercise on blood glucose level and pregnancy outcome in patients with gestational diabetes mellitus: a randomized controlled trial

Xie

Zhao

Meijing

et al. 2022

BMJ Open Diab Res Care

View full text Add to dashboard Cite

show abstract

“…Resistance exercise or combined aerobic and resistance exercise resulted in significant reductions in the required dosage of insulin in insulin-treated women with GDM. Combined training also reduced postprandial blood glucose [112]. Results from another meta-analysis also showed that exercising three times per week for 40-60 min at 65-75% of age-predicted maximum heart rate using cycling, walking or combined (circuit) training improved glycemic control in GDM patients and reduced the incidence of GDM in pregnant women with obesity [104].…”

Section: Which Type Of Exercise Can Results In the Most Favorable Glycemic And Health Benefits?mentioning

confidence: 92%

“…Meta-analytic data by Huang et al suggested that aerobic exercise reduced fasting and postprandial blood glucose and glycosylated hemoglobin levels in women with GDM [112]. Resistance exercise or combined aerobic and resistance exercise resulted in significant reductions in the required dosage of insulin in insulin-treated women with GDM.…”

Section: Which Type Of Exercise Can Results In the Most Favorable Glycemic And Health Benefits?mentioning

confidence: 99%

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus

et al. 2021

View full text Add to dashboard Cite

Gestational Diabetes Mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. Regular exercise is important for a healthy pregnancy and can lower the risk of developing GDM. For women with GDM, exercise is safe and can affect the pregnancy outcomes beneficially. A single exercise bout increases skeletal muscle glucose uptake, minimizing hyperglycemia. Regular exercise training promotes mitochondrial biogenesis, improves oxidative capacity, enhances insulin sensitivity and vascular function, and reduces systemic inflammation. Exercise may also aid in lowering the insulin dose in insulin-treated pregnant women. Despite these benefits, women with GDM are usually inactive or have poor participation in exercise training. Attractive individualized exercise programs that will increase adherence and result in optimal maternal and offspring benefits are needed. However, as women with GDM have a unique physiology, more attention is required during exercise prescription. This review (i) summarizes the cardiovascular and metabolic adaptations due to pregnancy and outlines the mechanisms through which exercise can improve glycemic control and overall health in insulin resistance states, (ii) presents the pathophysiological alterations induced by GDM that affect exercise responses, and (iii) highlights cardinal points of an exercise program for women with GDM.

show abstract

“… 27 The prevalence of GDM was significantly lower in the aerobic and resistant exercise group (2.1%; exercise involving skeletal muscle stretching by resistant band) compared with the aerobic exercise alone group (12.1%). A systematic review and meta-analysis study by Huang et al, 28 suggested that a potential mechanism underlying this association is that compared with the conventional treatment group, patients with GDM in the resistance exercise group had reduced the dosage of insulin needed, suggesting improved glucose metabolism due to resistance exercise.…”

Section: Discussionmentioning

confidence: 99%

Low-Intensity Exercise and Pregnancy Outcomes: An Examination in the Nurses' Health Study II

Yeo

Kang

2021

Women's Health Reports

View full text Add to dashboard Cite

Background: The benefit of low-intensity exercise (LIE) during pregnancy is poorly understood at a time when few women participate in moderate or vigorous exercise. Using data from the Nurses' Health Study II (NHSII), we tested the hypothesis that women who engaged in more LIE before and during pregnancy experience fewer pregnancy complications. Methods: Among 116,429 U.S. female registered nurses (25–42 years of age) who were enrolled in NHSII in 1989, we included participants (36–50 years of age) who reported in 2001 or 2005 that they were pregnant and completed questionnaires about pregnancy “low-intensity exercise (yoga, stretching, toning),” and who in 2009, provided a full pregnancy outcome history. Multivariable-adjusted relative risk (RR) and 95% confidence intervals (CIs) were calculated between LIE and adverse pregnancy outcomes using log-binomial regression models. Results: Among 225 eligible pregnant participants, 71 (31.6%) reported engaging in any LIE. LIE was associated with lower preterm birth, but not significantly associated with pregnancy loss or other adverse pregnancy outcomes. The RR for any LIE for preterm birth was 0.31 (95% CI: 0.09–1.07), with a significant dose–response association [RR = 0.65 (95% CI: 0.48–0.89) per every 30-minute session]. Some suggestive inverse associations were also observed for other adverse pregnancy outcomes: the RR for any LIE for low birthweight was 0.35 (95% CI: 0.08–1.48); for preeclampsia/gestational hypertension was 0.51 (95% CI: 0.13–1.96); and for gestational diabetes was 0.64 (95% CI: 0.25–1.64). Conclusion: Pregnant women can include yoga, stretching, and toning exercise for promoting wellbeing.

show abstract

Different exercises for pregnant women with gestational diabetes: a meta-analysis of randomized controlled trials

Cited by 14 publications

References 27 publications

Effects of resistance exercise on blood glucose level and pregnancy outcome in patients with gestational diabetes mellitus: a randomized controlled trial

Effects of resistance exercise on blood glucose level and pregnancy outcome in patients with gestational diabetes mellitus: a randomized controlled trial

Exercise as a Therapeutic Intervention in Gestational Diabetes Mellitus

Low-Intensity Exercise and Pregnancy Outcomes: An Examination in the Nurses' Health Study II

Contact Info

Product

Resources

About