Different Forms of Decellularized Tissues and Their Characteristics, Applications in Tissue Repair as Well as Performance Optimization

Da, Lincui; Lei, Xiongxin; Song, Yuting; Huang, Yi-Zhou; Xie, Huiqi

doi:10.1007/978-981-33-6962-7_3

Decellularized Materials 2021

DOI: 10.1007/978-981-33-6962-7_3

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Different Forms of Decellularized Tissues and Their Characteristics, Applications in Tissue Repair as Well as Performance Optimization

Lincui Da

Xiongxin Lei

Yuting Song

et al.

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2024

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Cited by 1 publication

References 336 publications

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A Novel Human Amniotic Membrane Suspension Improves the Therapeutic Effect of Mesenchymal Stem Cells on Myocardial Infarction in Rats

Li,

Zhang,

Wang

et al. 2024

Advanced NanoBiomed Research

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Mesenchymal stem cell (MSC) therapy aids cardiac repair and regeneration, but the low rate of MSC survival and engulfment in the infarcted heart remains a major obstacle for routine clinical application. Here, an injectable suspension of human acellular amniotic membrane (HAAM) that may serve as synergistic cell delivery vehicle for the treatment of myocardial infarction (MI) by improving MSC homing and survival is developed. The results demonstrate that compared with MSC transplantation alone, HAAM‐loaded MSCs have higher survival and engraftment rates in infarcted tissue, alleviated hypoxia‐induced myocardial damage, achieved higher improvements in cardiac function, promoted angiogenesis, and reduced myocardial fibrosis. In addition, HAAM‐loaded MSCs increase N‐cadherin levels and thereby enhance the efficacy of MSCs in treating MI. This study provides a new approach for MSC‐based cardiac repair and regeneration.

show abstract

A Novel Human Amniotic Membrane Suspension Improves the Therapeutic Effect of Mesenchymal Stem Cells on Myocardial Infarction in Rats

Li,

Zhang,

Wang

et al. 2024

Advanced NanoBiomed Research

View full text Add to dashboard Cite

show abstract

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Different Forms of Decellularized Tissues and Their Characteristics, Applications in Tissue Repair as Well as Performance Optimization

Cited by 1 publication

References 336 publications

A Novel Human Amniotic Membrane Suspension Improves the Therapeutic Effect of Mesenchymal Stem Cells on Myocardial Infarction in Rats

A Novel Human Amniotic Membrane Suspension Improves the Therapeutic Effect of Mesenchymal Stem Cells on Myocardial Infarction in Rats

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