Different Prognostic Values of Tumour and Nodal Response to Neoadjuvant Chemotherapy Depending on Subtypes of Inflammatory Breast Cancer, a 317 Patient-Study

Rogé, Maximilien; Salleron, Julia; Kirova, Youlia; Guigo, Marin; Cailleteau, Axel; Lévy, Christelle; Leheurteur, Marianne; Nebbache, Rafik; Campo, Eleonor Rivin del; Lazarescu, Ioana; Servagi, S.; Aumont, Maud; Thariat, Juliette; Thureau, S.

doi:10.3390/cancers14163928

Cited by 7 publications

(1 citation statement)

References 28 publications

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“…The specific manifestation was that the morphology of the cancer cells was irregular, the whole cell was swollen, and the boundary was unclear. It could be observed that vacuoles appeared in the cytoplasm, and the nucleus was enlarged or showed deep staining and deformity ( 67 ). The cases diagnosed as pCR by postoperative histopathology have been confirmed by multiple studies ( 68 ), and their recurrence-free survival rate and overall survival rate are better than those of cases that have not achieved complete pathological remission.…”

Section: Microscopic Pathologymentioning

confidence: 99%

Neoadjuvant chemotherapy for breast cancer: an evaluation of its efficacy and research progress

Chen,

Qi,

Wang

2023

Front. Oncol.

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Neoadjuvant chemotherapy (NAC) for breast cancer is widely used in the clinical setting to improve the chance of surgery, breast conservation and quality of life for patients with advanced breast cancer. A more accurate efficacy evaluation system is important for the decision of surgery timing and chemotherapy regimen implementation. However, current methods, encompassing imaging techniques such as ultrasound and MRI, along with non-imaging approaches like pathological evaluations, often fall short in accurately depicting the therapeutic effects of NAC. Imaging techniques are subjective and only reflect macroscopic morphological changes, while pathological evaluation is the gold standard for efficacy assessment but has the disadvantage of delayed results. In an effort to identify assessment methods that align more closely with real-world clinical demands, this paper provides an in-depth exploration of the principles and clinical applications of various assessment approaches in the neoadjuvant chemotherapy process.

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Section: Microscopic Pathologymentioning

confidence: 99%