Different retinopathy of prematurity severity and outcomes in triplets: A case report

Abstract

In this case report, we discuss the presentation of retinopathy of prematurity in triplets born at 25 + 3 weeks gestational age of whom each had a different birth weight, weight gain and treatment requirements. Triplet A weighed 800 g and his retinopathy of prematurity had resolved with no intervention. Triplet B weighed 630 g at birth and he required bilateral intravitreal ranibizumab injection at 32 + 6 weeks. Triplet C weighed 520 g and required bilateral intravitreal ranibizumab injection at 36 weeks, but after 5 weeks he had recurrence which was treated with bilateral diode laser. Triplet C had the poorest weight gain. The main differences between the triplets are the birth weight and the weight gain. Furthermore, refraction was performed at 10 months; triplet A had a hyperopia of +1.25 spherical equivalent in both eyes, triplet B had mild myopia of −0.25 spherical equivalent and triplet C had a myopia of −3.00 spherical equivalent in the right eye and −2.75 spherical equivalent in the left eye.

A tale of orbital cellulitis and retinopathy of prematurity in an infant: First case report

“…The severity of ROP may differ among babies born at the same gestational age and even among babies born out of the same pregnancy. Amro et al 7 reported a case of three triplets who presented for timely evaluation and were detected with differential retinopathies. The first kid’s retinopathy resolved with no intervention, the second kid required intravitreal ranibizumab, and the third kid required a bilateral diode laser.…”