2020
DOI: 10.1186/s41984-020-00078-7
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Different strategies in the management of thalamic space-occupying lesions

Abstract: Introduction: Thalamic space-occupying lesions (SOL) are considered challenging for microsurgical removal. Unfortunately, the pathological features of lesions occurring in the thalamic region are different with a wide variation in clinical behavior and outcome. Although microsurgery is still the gold standard in the management of these lesions through different approaches, questions remain whether surgery is feasible and safe in these patients and what are the alternatives? It is well known that stereotactic t… Show more

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Cited by 3 publications
(2 citation statements)
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“…Stereotaxy was used in 18 cases; the most common clinical presentation was hemiparesis in 21 cases (60 percent), followed by manifestation of increased ICP (headache, nausea, and vomiting) in 13 cases (37 percent), hemiparethesia in 3 cases (8.5 percent), signs of meningeal irritation in 1 case (3%), and convulsions in 1 case (3%). 7 As for post-operative clinical results in our study, majority (81.8%) of patients presenting with headache preoperatively had improved postoperatively, as for those presented by dysphasia, 44% (4 patients) of them already improved as a result of the operation. Regarding patients presenting with symptoms of increased intracranial pressure; the 3 patients who presented with repeated vomiting had improved.…”
Section: Discussionsupporting
confidence: 58%
See 1 more Smart Citation
“…Stereotaxy was used in 18 cases; the most common clinical presentation was hemiparesis in 21 cases (60 percent), followed by manifestation of increased ICP (headache, nausea, and vomiting) in 13 cases (37 percent), hemiparethesia in 3 cases (8.5 percent), signs of meningeal irritation in 1 case (3%), and convulsions in 1 case (3%). 7 As for post-operative clinical results in our study, majority (81.8%) of patients presenting with headache preoperatively had improved postoperatively, as for those presented by dysphasia, 44% (4 patients) of them already improved as a result of the operation. Regarding patients presenting with symptoms of increased intracranial pressure; the 3 patients who presented with repeated vomiting had improved.…”
Section: Discussionsupporting
confidence: 58%
“…These two lesions were highgrade gliomas, which might explain the worsening but is impossible to verify statistically. 7 Esquenazi et al, mentioned that despite normal postoperative imaging and the absence of tumoral bleeding, postoperative impairments in deeply localized lesions may emerge. In the case of tumor edema, the intimate linkage of the thalamus to important functional regions might result in neurological impairments after biopsy or surgical debulking.…”
Section: Discussionmentioning
confidence: 99%