2010
DOI: 10.1097/bth.0b013e3181dcaaa8
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Different Surgical Approaches to Treat Chronic Tophaceous Gout in the Hand: Our Experience

Abstract: Chronic tophaceous gout is a disabling erosive arthritis characterized by an elevated serum urate concentration, recurrent attacks of arthritis, and deposits of monosodium urate crystals in synovial fluids. Tophi, ulcerations of the overlying skin, and fissures of the interarticular cartilage may occur in advanced stages, combined with deformities of the joints and decreased active joint flexion and extension. Although the timely use of allopurinol is associated with a decrease in the frequency of deposits of … Show more

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Cited by 13 publications
(14 citation statements)
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“…The main indication for surgery in patients with tophaceous gout is sepsis or infection of ulcerated tophi, followed by mechanical problems, confirmation of diagnosis and pain control [12]. Removal of tophaceous deposits from the hands can be achieved through tenosynovectomy for heavily infiltrated tendons, through a soft-tissue shaving technique for heavy skin infiltration with ulceration and draining fissures [13], or through more complex surgical approaches involving large skin incisions and excision of the tophi [14]. A hydrosurgery system applying a highly pressurized saline stream has also been used with good results for the debridement of tophi [15].…”
Section: Discussionmentioning
confidence: 99%
“…The main indication for surgery in patients with tophaceous gout is sepsis or infection of ulcerated tophi, followed by mechanical problems, confirmation of diagnosis and pain control [12]. Removal of tophaceous deposits from the hands can be achieved through tenosynovectomy for heavily infiltrated tendons, through a soft-tissue shaving technique for heavy skin infiltration with ulceration and draining fissures [13], or through more complex surgical approaches involving large skin incisions and excision of the tophi [14]. A hydrosurgery system applying a highly pressurized saline stream has also been used with good results for the debridement of tophi [15].…”
Section: Discussionmentioning
confidence: 99%
“…They closely resemble a nodular lesion arising from a connective tissue disorder such as rheumatoid nodules, and deposits such as skin calcification, chondrocalcinosis, xanthoma, and secondary deposits from kidney and lung cancers, etc. [2,8,9]. Atypical presentation with concomitant giant cell tumor of soft tissue or as a bullous lesion also has been reported [10,11].…”
Section: Results Of Literature Overviewmentioning
confidence: 93%
“…In such cases, surgical management should be discussed to restore and improve the joint function, reduce symptomatic discomfort, and lower the risk of infection when the overlying skin becomes ulcerated. [11][12][13] To avoid compromising neurovascular structures, tendons, and skin, one should not attempt excision of the whole tophus. 14,15 Tophi that are adherent to the skin or tendons are gently curetted or excised sharply.…”
Section: Discussionmentioning
confidence: 99%