Different temporal windows for contextual fear memory destabilisation in the amygdala and hippocampus

Abstract

2 15Abstract 16 17 Reconsolidation is a process in which re-exposure to a reminder causes a previously acquired 18 memory to undergo a process of destabilisation followed by subsequent restabilisation. Different 19 molecular mechanisms have been postulated for destabilisation in the amygdala and hippocampus, 20 including CB1 receptor activation, protein degradation and AMPA receptor exchange; however, most 21 of the amygdala studies have used pre-re-exposure interventions, while those in the hippocampus