Quantitative versions (i.e., taking into account a suitable ``distance'' of a set from being a sphere) of the
isoperimetric inequality are obtained, in the spirit of a paper by Fusco, Maggi and Pratelli (Ann. Math. 2008), for a class of not necessarily
convex sets called sets with positive reach.
Our work is based on geometrical results on sets with positive reach, obtained using methods of both
nonsmooth analysis and geometric measure theory